biostudies-literatureGuha ANCATS NIH HHSAmerican Heart Association-American Stroke AssociationNHLBI NIH HHSNCI NIH HHSNIH300-312https://www.ebi.ac.uk/biostudies/studies/S-EPMC8914878biostudies-literatureUnknown43(4)<h4>Aims</h4>The national incidence, risk factors, and associated mortality of atrial fibrillation (AF) in breast cancer patients are unknown.<h4>Methods and results</h4>Using the Surveillance, Epidemiology, and End Results-Medicare-linked database, we identified females, ≥66 years old, with a new primary diagnosis of breast cancer from 2007 through 2014. These patients were individually matched 1:1 to Medicare enrolees without cancer, and each pair was followed for 1 year to identify a primary outcome of AF. Cumulative incidence was calculated using competing risk survival statistics. Following this, identifying risk factors of AF among breast cancer patients was conducted using the adjusted Cox proportional hazards model. Finally, Kaplan-Meier methods and adjusted Cox proportional hazardEuropean heart journalIncidence, risk factors, and mortality of atrial fibrillation in breast cancer: a SEER-Medicare analysis.PMC8914878K12 CA133250P30 CA016058K12-CA133250K23 HL155890K24 HL14852116EIA26410001UL1 TR001863K23-HL155890P30 CA014236Guha AWeintraub NLAddison DFradley MGDent SFAlonso ALustberg MBfalseIncidence, risk factors, and mortality of atrial fibrillation in breast cancer: a SEER-Medicare analysis.<h4>Aims</h4>The national incidence, risk factors, and associated mortality of atrial fibrillation (AF) in breast cancer patients are unknown.<h4>Methods and results</h4>Using the Surveillance, Epidemiology, and End Results-Medicare-linked database, we identified females, ≥66 years old, with a new primary diagnosis of breast cancer from 2007 through 2014. These patients were individually matched 1:1 to Medicare enrolees without cancer, and each pair was followed for 1 year to identify a primary outcome of AF. Cumulative incidence was calculated using competing risk survival statistics. Following this, identifying risk factors of AF among breast cancer patients was conducted using the adjusted Cox proportional hazards model. Finally, Kaplan-Meier methods and adjusted Cox proportional hazard2022-01-01T00:00:00Z2022 Jan2025-04-05T12:31:53.194Z2025-04-05T12:31:53.194ZS-EPMC89148783479112310.1093/eurheartj/ehab745