{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Hierl KV"],"funding":["Bundesministerium für Wirtschaft und Technologie"],"pagination":["e0265324"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8916626"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["17(3)"],"pubmed_abstract":["<h4>Purpose</h4>This study aimed at evaluating the orbital anatomy of patients concerning the relevance of orbital anatomy in the etiology of EO (endocrine orbitopathy) and exophthalmos utilizing a novel approach regarding three-dimensional measurements. Furthermore, sexual dimorphism in orbital anatomy was analyzed.<h4>Methods</h4>Orbital anatomy of 123 Caucasian patients (52 with EO, 71 without EO) was examined using computed tomographic data and FAT software for 3-D cephalometry. Using 56 anatomical landmarks, 20 angles and 155 distances were measured. MEDAS software was used for performing connected and unconnected t-tests and Spearman´s rank correlation test to evaluate interrelations and differences.<h4>Results</h4>Orbital anatomy was highly symmetrical with a mean side difference of"],"journal":["PloS one"],"pubmed_title":["3-D cephalometry of the the orbit regarding endocrine orbitopathy, exophthalmos, and sex."],"pmcid":["PMC8916626"],"funding_grant_id":["ZIM KF2036708SS0"],"pubmed_authors":["Krause M","Hierl KV","Sterker I","Kruber D"],"additional_accession":[]},"is_claimable":false,"name":"3-D cephalometry of the the orbit regarding endocrine orbitopathy, exophthalmos, and sex.","description":"<h4>Purpose</h4>This study aimed at evaluating the orbital anatomy of patients concerning the relevance of orbital anatomy in the etiology of EO (endocrine orbitopathy) and exophthalmos utilizing a novel approach regarding three-dimensional measurements. Furthermore, sexual dimorphism in orbital anatomy was analyzed.<h4>Methods</h4>Orbital anatomy of 123 Caucasian patients (52 with EO, 71 without EO) was examined using computed tomographic data and FAT software for 3-D cephalometry. Using 56 anatomical landmarks, 20 angles and 155 distances were measured. MEDAS software was used for performing connected and unconnected t-tests and Spearman´s rank correlation test to evaluate interrelations and differences.<h4>Results</h4>Orbital anatomy was highly symmetrical with a mean side difference of","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022","modification":"2025-04-26T04:38:02.894Z","creation":"2025-04-26T04:38:02.894Z"},"accession":"S-EPMC8916626","cross_references":{"pubmed":["35275980"],"doi":["10.1371/journal.pone.0265324"]}}