<HashMap><database>biostudies-literature</database><scores/><additional><submitter>Argabright ST</submitter><funding>NIDA NIH HHS</funding><funding>NIMH NIH HHS</funding><pagination>686-697</pagination><full_dataset_link>https://www.ebi.ac.uk/biostudies/studies/S-EPMC8917360</full_dataset_link><repository>biostudies-literature</repository><omics_type>Unknown</omics_type><volume>61(5)</volume><pubmed_abstract>&lt;h4>Objective&lt;/h4>Youth suicide rates in the United States have been increasing in recent years, especially in Black Americans, the reasons for which are unclear. Environmental adversity is key in youth suicidality; hence there is a need to study stressors that have a disproportionate impact on Black youths. We aimed to disentangle the unique contribution of racial/ethnic discrimination from other adversities associated with childhood suicidal ideation and attempts (suicidality).&lt;h4>Method&lt;/h4>We analyzed data from the Adolescent Brain Cognitive Development (ABCD) Study, which included a large, diverse sample of US children (N = 11,235, mean age 10.9 years, 20.2% Black), assessed for multiple environmental adversities including discrimination. Multivariate regression models tested the association of self-reported racial/ethnic discrimination with suicidality, covarying for multiple confounders including other discrimination types (toward non-US-born individuals, sexual orientation-based, and weight-based). Matched analyses contrasted effects of racial/ethnic discrimination and racial identity on suicidality.&lt;h4>Results&lt;/h4>Black youths reported more discrimination and higher suicidality rates than non-Black youths. High racial/ethnic discrimination was positively and significantly associated with suicidality, adjusting for other discrimination types (odds ratio = 2.6, 95% CI = 2.1-3.2). Findings remained significant after adjusting for multiple suicidality risk factors. Once experienced, racial/ethnic discrimination was similarly associated with suicidality in White, Black, and Hispanic youths. Matched analyses revealed that racial/ethnic discrimination was associated with suicidality (relative risk = 2.7, 95% CI = 2-3.5), whereas Black race was not (relative risk = 0.9, 95% CI = 0.7-1.2).&lt;h4>Conclusion&lt;/h4>Racial/ethnic discrimination is disproportionately experienced by Black children, and is associated with preadolescent suicidality, over and above other adversities. Findings highlight the need to address discrimination as part of suicide prevention strategies. Cross-sectional design hampers causal inferences.</pubmed_abstract><journal>Journal of the American Academy of Child and Adolescent Psychiatry</journal><pubmed_title>Association Between Discrimination Stress and Suicidality in Preadolescent Children.</pubmed_title><pmcid>PMC8917360</pmcid><funding_grant_id>U01 DA041117</funding_grant_id><funding_grant_id>U24 DA041123</funding_grant_id><funding_grant_id>U24 DA041147</funding_grant_id><funding_grant_id>U01 DA041174</funding_grant_id><funding_grant_id>U01 DA041134</funding_grant_id><funding_grant_id>U01 DA041156</funding_grant_id><funding_grant_id>U01 DA041093</funding_grant_id><funding_grant_id>U01 DA051037</funding_grant_id><funding_grant_id>R21 MH123916</funding_grant_id><funding_grant_id>U01 DA041106</funding_grant_id><funding_grant_id>U01 DA041028</funding_grant_id><funding_grant_id>R01 MH117014</funding_grant_id><funding_grant_id>K23 MH120437</funding_grant_id><funding_grant_id>U01 DA041089</funding_grant_id><funding_grant_id>U01 DA041022</funding_grant_id><funding_grant_id>U01 DA041120</funding_grant_id><funding_grant_id>U01 DA041148</funding_grant_id><funding_grant_id>U01 DA041048</funding_grant_id><funding_grant_id>U01 DA041025</funding_grant_id><funding_grant_id>U01 DA051039</funding_grant_id><funding_grant_id>U01 DA051016</funding_grant_id><funding_grant_id>U01 DA051038</funding_grant_id><funding_grant_id>U01 DA051018</funding_grant_id><funding_grant_id>U01 DA050988</funding_grant_id><funding_grant_id>U01 DA050987</funding_grant_id><funding_grant_id>U01 DA050989</funding_grant_id><pubmed_authors>Gur RC</pubmed_authors><pubmed_authors>Benton TD</pubmed_authors><pubmed_authors>Gur RE</pubmed_authors><pubmed_authors>DiDomenico GE</pubmed_authors><pubmed_authors>Njoroge WFM</pubmed_authors><pubmed_authors>Moore TM</pubmed_authors><pubmed_authors>Guloksuz S</pubmed_authors><pubmed_authors>Argabright ST</pubmed_authors><pubmed_authors>Barzilay R</pubmed_authors><pubmed_authors>Visoki E</pubmed_authors><pubmed_authors>Ryan DT</pubmed_authors><pubmed_authors>Taylor JH</pubmed_authors></additional><is_claimable>false</is_claimable><name>Association Between Discrimination Stress and Suicidality in Preadolescent Children.</name><description>&lt;h4>Objective&lt;/h4>Youth suicide rates in the United States have been increasing in recent years, especially in Black Americans, the reasons for which are unclear. Environmental adversity is key in youth suicidality; hence there is a need to study stressors that have a disproportionate impact on Black youths. We aimed to disentangle the unique contribution of racial/ethnic discrimination from other adversities associated with childhood suicidal ideation and attempts (suicidality).&lt;h4>Method&lt;/h4>We analyzed data from the Adolescent Brain Cognitive Development (ABCD) Study, which included a large, diverse sample of US children (N = 11,235, mean age 10.9 years, 20.2% Black), assessed for multiple environmental adversities including discrimination. Multivariate regression models tested the association of self-reported racial/ethnic discrimination with suicidality, covarying for multiple confounders including other discrimination types (toward non-US-born individuals, sexual orientation-based, and weight-based). Matched analyses contrasted effects of racial/ethnic discrimination and racial identity on suicidality.&lt;h4>Results&lt;/h4>Black youths reported more discrimination and higher suicidality rates than non-Black youths. High racial/ethnic discrimination was positively and significantly associated with suicidality, adjusting for other discrimination types (odds ratio = 2.6, 95% CI = 2.1-3.2). Findings remained significant after adjusting for multiple suicidality risk factors. Once experienced, racial/ethnic discrimination was similarly associated with suicidality in White, Black, and Hispanic youths. Matched analyses revealed that racial/ethnic discrimination was associated with suicidality (relative risk = 2.7, 95% CI = 2-3.5), whereas Black race was not (relative risk = 0.9, 95% CI = 0.7-1.2).&lt;h4>Conclusion&lt;/h4>Racial/ethnic discrimination is disproportionately experienced by Black children, and is associated with preadolescent suicidality, over and above other adversities. Findings highlight the need to address discrimination as part of suicide prevention strategies. Cross-sectional design hampers causal inferences.</description><dates><release>2022-01-01T00:00:00Z</release><publication>2022 May</publication><modification>2026-06-03T13:26:52.82Z</modification><creation>2025-04-19T13:31:21.812Z</creation></dates><accession>S-EPMC8917360</accession><cross_references><pubmed>34425231</pubmed><doi>10.1016/j.jaac.2021.08.011</doi></cross_references></HashMap>