{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["130(3)"],"submitter":["Schillemans T"],"pubmed_abstract":["<h4>Background</h4>Per- and polyfluoroalkyl substances (PFAS) are widespread and persistent pollutants that have been associated with elevated cholesterol levels. However, data on incident cardiovascular disease (CVD) is lacking.<h4>Objectives</h4>We investigated the association of exposure to PFAS with risk of myocardial infarction and stroke and, subsidiary, with baseline blood lipids.<h4>Methods</h4>This population-based nested case-control study included first incident myocardial infarction and stroke cases with matched controls from two Swedish cohorts: the Swedish Mammography Cohort-Clinical (SMC-C) and the Cohort of 60-year-olds (60YO). Baseline blood sampling occurred during 2003-2009 and 1997-1999 with follow-up through 2017 and 2014 for the SMC-C and the 60YO, respectively. Eight"],"journal":["Environmental health perspectives"],"pagination":["37007"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8919955"],"repository":["biostudies-literature"],"pubmed_title":["Per- and Polyfluoroalkyl Substances and Risk of Myocardial Infarction and Stroke: A Nested Case-Control Study in Sweden."],"pmcid":["PMC8919955"],"pubmed_authors":["Akesson A","Donat-Vargas C","Schillemans T","de Faire U","Wolk A","Lindh CH","Leander K"],"additional_accession":[]},"is_claimable":false,"name":"Per- and Polyfluoroalkyl Substances and Risk of Myocardial Infarction and Stroke: A Nested Case-Control Study in Sweden.","description":"<h4>Background</h4>Per- and polyfluoroalkyl substances (PFAS) are widespread and persistent pollutants that have been associated with elevated cholesterol levels. However, data on incident cardiovascular disease (CVD) is lacking.<h4>Objectives</h4>We investigated the association of exposure to PFAS with risk of myocardial infarction and stroke and, subsidiary, with baseline blood lipids.<h4>Methods</h4>This population-based nested case-control study included first incident myocardial infarction and stroke cases with matched controls from two Swedish cohorts: the Swedish Mammography Cohort-Clinical (SMC-C) and the Cohort of 60-year-olds (60YO). Baseline blood sampling occurred during 2003-2009 and 1997-1999 with follow-up through 2017 and 2014 for the SMC-C and the 60YO, respectively. Eight","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Mar","modification":"2025-04-26T10:14:14.251Z","creation":"2025-04-06T13:16:22.16Z"},"accession":"S-EPMC8919955","cross_references":{"pubmed":["35285690"],"doi":["10.1289/EHP9791"]}}