biostudies-literatureYilmaz MDornier MedTech Laser GmbH (DE)Albert-Ludwigs-Universität Freiburg im BreisgauDornier MedTech Laser GmbH601-606https://www.ebi.ac.uk/biostudies/studies/S-EPMC8921029biostudies-literatureUnknown40(2)<h4>Purpose</h4>The aim of this study was to compare the enucleation performances of four different types of laser devices in an ex-vivo experiment: a novel, pulsed Tm:YAG solid-state laser evaluation model (p-Tm:YAG), chopped thulium fibre laser (TFL), low-power Ho:YAG laser (LP-Ho:YAG), and a high-power Ho:YAG laser (HP-Ho:YAG).<h4>Methods</h4>Our primary aim was to endoscopically separate the fascial layers of a porcine belly using laser fibres within a time period of 60 s. The size of a "tissue pocket" was assessed numerically. The enucleation characteristics reflecting the surgeon's experience were evaluated via the NASA Task Load Index (TLX) questionnaire and a questionnaire based on Likert scale.<h4>Results</h4>HP-Ho:YAG achieved with the available laser settings the largest overall "tissue pocket" (31.5 cm²) followed by p-Tm:YAG (15 cm²), TFL (12 cm²), and LP-Ho:YAG (6 cm²). The coagulation performances of p-Tm:YAG and TFL were rated the best. In the performance evaluation by the Likert questionnaire, HP-Ho:YAG (average score of 4.06) was rated highest, followed by p-Tm:YAG (3.94), TFL (3.38), and LP-Ho:YAG (3.25). The evaluation of the NASA-TLX performance questionnaire revealed average scores for HP-Ho:YAG, LP-Ho:YAG, TFL and p-Tm:YAG of 4.38, 4.09, 3.92 and 3.90, respectively.<h4>Conclusion</h4>We are the first to compare different laser devices and settings in an ex-vivo study. We found that the surgeons were most satisfied with the HP-Ho:YAG laser device, followed by the p-Tm:YAG. These findings could be highly relevant for future research and for the practical utilisation of laser systems in endourology.World journal of urologyExperimental ex-vivo performance study comparing a novel, pulsed thulium solid-state laser, chopped thulium fibre laser, low and high-power holmium:YAG laser for endoscopic enucleation of the prostate.PMC8921029(ZVK20200072801 (1040185101))Gratzke CEsser JPetzold RKraft LSuarez-Ibarrola RMiernik AYilmaz MSigle AfalseExperimental ex-vivo performance study comparing a novel, pulsed thulium solid-state laser, chopped thulium fibre laser, low and high-power holmium:YAG laser for endoscopic enucleation of the prostate.<h4>Purpose</h4>The aim of this study was to compare the enucleation performances of four different types of laser devices in an ex-vivo experiment: a novel, pulsed Tm:YAG solid-state laser evaluation model (p-Tm:YAG), chopped thulium fibre laser (TFL), low-power Ho:YAG laser (LP-Ho:YAG), and a high-power Ho:YAG laser (HP-Ho:YAG).<h4>Methods</h4>Our primary aim was to endoscopically separate the fascial layers of a porcine belly using laser fibres within a time period of 60 s. The size of a "tissue pocket" was assessed numerically. The enucleation characteristics reflecting the surgeon's experience were evaluated via the NASA Task Load Index (TLX) questionnaire and a questionnaire based on Likert scale.<h4>Results</h4>HP-Ho:YAG achieved with the available laser settings the largest overall "tissue pocket" (31.5 cm²) followed by p-Tm:YAG (15 cm²), TFL (12 cm²), and LP-Ho:YAG (6 cm²). The coagulation performances of p-Tm:YAG and TFL were rated the best. In the performance evaluation by the Likert questionnaire, HP-Ho:YAG (average score of 4.06) was rated highest, followed by p-Tm:YAG (3.94), TFL (3.38), and LP-Ho:YAG (3.25). The evaluation of the NASA-TLX performance questionnaire revealed average scores for HP-Ho:YAG, LP-Ho:YAG, TFL and p-Tm:YAG of 4.38, 4.09, 3.92 and 3.90, respectively.<h4>Conclusion</h4>We are the first to compare different laser devices and settings in an ex-vivo study. We found that the surgeons were most satisfied with the HP-Ho:YAG laser device, followed by the p-Tm:YAG. These findings could be highly relevant for future research and for the practical utilisation of laser systems in endourology.2022-01-01T00:00:00Z2022 Feb2025-04-22T03:57:50.206Z2025-02-19T02:01:53.576ZS-EPMC89210293447795410.1007/s00345-021-03825-z