{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Mauck MC"],"funding":["University of North Carolina Department of Anesthesiology","NICHD NIH HHS","DC Firefighters Burn Foundation","Eunice Kennedy Shriver National Institute Of Child Health & Human Development","National Institutes of Health","Jaycee Burn Center","NIH HHS"],"pagination":["1186-1191"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8921735"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["42(6)"],"pubmed_abstract":["Major thermal burn injuries result in approximately 40,000 hospitalizations in the United States each year. Chronic pain affects up to 60% of burn survivors, and Black Americans have worse chronic pain outcomes than White Americans. Mechanisms of chronic pain pathogenesis after burn injury, and accounting for these racial differences, remain poorly understood. Due to socioeconomic disadvantage and differences in skin absorption, Black Americans have an increased prevalence of Vitamin D deficiency. We hypothesized that peritraumatic Vitamin D levels predict chronic pain outcomes after burn injury and contribute to racial differences in pain outcomes. Among burn survivors (n = 77, 52% White, 48% Black, 77% male), peritraumatic Vitamin D levels were more likely to be deficient in Blacks vs Wh"],"journal":["Journal of burn care & research : official publication of the American Burn Association"],"pubmed_title":["Peritraumatic Vitamin D Levels Predict Chronic Pain Severity and Contribute to Racial Differences in Pain Outcomes Following Major Thermal Burn Injury."],"pmcid":["PMC8921735"],"funding_grant_id":["K12HD001441","K12 HD001441","UNC BIRCWH 3K12HD001441-18S1"],"pubmed_authors":["Tungate A","Shupp JW","McLean SA","Williams FN","McGrath KV","Cairns BA","Karlnoski R","Smith DJ","Jones SW","Mauck MC","Barton CE"],"additional_accession":[]},"is_claimable":false,"name":"Peritraumatic Vitamin D Levels Predict Chronic Pain Severity and Contribute to Racial Differences in Pain Outcomes Following Major Thermal Burn Injury.","description":"Major thermal burn injuries result in approximately 40,000 hospitalizations in the United States each year. Chronic pain affects up to 60% of burn survivors, and Black Americans have worse chronic pain outcomes than White Americans. Mechanisms of chronic pain pathogenesis after burn injury, and accounting for these racial differences, remain poorly understood. Due to socioeconomic disadvantage and differences in skin absorption, Black Americans have an increased prevalence of Vitamin D deficiency. We hypothesized that peritraumatic Vitamin D levels predict chronic pain outcomes after burn injury and contribute to racial differences in pain outcomes. Among burn survivors (n = 77, 52% White, 48% Black, 77% male), peritraumatic Vitamin D levels were more likely to be deficient in Blacks vs Wh","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Nov","modification":"2025-04-21T15:42:36.414Z","creation":"2025-04-21T15:42:36.414Z"},"accession":"S-EPMC8921735","cross_references":{"pubmed":["33564878"],"doi":["10.1093/jbcr/irab031"]}}