biostudies-literatureLin XLNational Natural Science Foundation of China282-290https://www.ebi.ac.uk/biostudies/studies/S-EPMC8922537biostudies-literatureUnknown45(3)<h4>Background</h4>Acute myocardial infarction (AMI) is the main cause of death and disability in cardiovascular and cerebrovascular diseases. Both the Global Registry of Acute Coronary Events (Grace) score and high-sensitivity C-reactive protein (hs-CRP) were associated with prognosis in patients with AMI. However, whether the addition of the hs-CRP to Grace risk score could improve the predictive power of Grace risk score on the prognosis of patients with AMI is unclear.<h4>Hypothesis</h4>We hypothesized that the inclusion of hs-CRP in the Grace risk score could improve the ability to correctly distinguish the occurrence of in-hospital outcomes.<h4>Methods</h4>We retrospectively enrolled 1804 patients with AMI in the final analysis. Patients were divided into four groups by hs-CRP quartiClinical cardiologyAdmission high-sensitivity C-reactive protein levels improve the Grace risk score prediction on in-hospital outcomes in acute myocardial infarction patients.PMC89225378177149481971302Sun HXLi FQZhao JYLin XLZhao DHLiu JHFan QfalseAdmission high-sensitivity C-reactive protein levels improve the Grace risk score prediction on in-hospital outcomes in acute myocardial infarction patients.<h4>Background</h4>Acute myocardial infarction (AMI) is the main cause of death and disability in cardiovascular and cerebrovascular diseases. Both the Global Registry of Acute Coronary Events (Grace) score and high-sensitivity C-reactive protein (hs-CRP) were associated with prognosis in patients with AMI. However, whether the addition of the hs-CRP to Grace risk score could improve the predictive power of Grace risk score on the prognosis of patients with AMI is unclear.<h4>Hypothesis</h4>We hypothesized that the inclusion of hs-CRP in the Grace risk score could improve the ability to correctly distinguish the occurrence of in-hospital outcomes.<h4>Methods</h4>We retrospectively enrolled 1804 patients with AMI in the final analysis. Patients were divided into four groups by hs-CRP quarti2022-01-01T00:00:00Z2022 Mar2025-04-22T07:45:06.668Z2025-04-05T22:18:22.404ZS-EPMC89225373506690110.1002/clc.23749