{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Kaya-Zeeb S"],"funding":["Deutsche Forschungsgemeinschaft"],"pagination":["e74334"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8923666"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["11"],"pubmed_abstract":["In times of environmental change species have two options to survive: they either relocate to a new habitat or they adapt to the altered environment. Adaptation requires physiological plasticity and provides a selection benefit. In this regard, the Western honeybee (Apis mellifera) protrudes with its thermoregulatory capabilities, which enables a nearly worldwide distribution. Especially in the cold, shivering thermogenesis enables foraging as well as proper brood development and thus survival. In this study, we present octopamine signaling as a neurochemical prerequisite for honeybee thermogenesis: we were able to induce hypothermia by depleting octopamine in the flight muscles. Additionally, we could restore the ability to increase body temperature by administering octopamine. Thus, we c"],"journal":["eLife"],"pubmed_title":["Octopamine drives honeybee thermogenesis."],"pmcid":["PMC8923666"],"funding_grant_id":["TH2264/2-1"],"pubmed_authors":["Straßburger M","Seifert R","Kaya-Zeeb S","Bahre H","Thamm M","Bayer J","Engelmayer L","Scherf-Clavel O"],"additional_accession":[]},"is_claimable":false,"name":"Octopamine drives honeybee thermogenesis.","description":"In times of environmental change species have two options to survive: they either relocate to a new habitat or they adapt to the altered environment. Adaptation requires physiological plasticity and provides a selection benefit. In this regard, the Western honeybee (Apis mellifera) protrudes with its thermoregulatory capabilities, which enables a nearly worldwide distribution. Especially in the cold, shivering thermogenesis enables foraging as well as proper brood development and thus survival. In this study, we present octopamine signaling as a neurochemical prerequisite for honeybee thermogenesis: we were able to induce hypothermia by depleting octopamine in the flight muscles. Additionally, we could restore the ability to increase body temperature by administering octopamine. Thus, we c","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Mar","modification":"2025-04-19T21:44:24.411Z","creation":"2025-04-19T21:44:24.411Z"},"accession":"S-EPMC8923666","cross_references":{"pubmed":["35289743"],"doi":["10.7554/eLife.74334"]}}