{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Wang Y"],"funding":["National Natural Science Foundation of China","China Postdoctoral Science Foundation","Heilongjiang Provincial Postdoctoral Science Foundation"],"pagination":["809747"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8924052"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["10"],"pubmed_abstract":["Bladder cancer (BC) is a highly prevalent cancer form of the genitourinary system; however, the effective biomarkers are still ambiguous and deserve deeper investigation. Long non-coding RNA (lncRNA) occupies a prominent position in tumor biology and immunology, and ferroptosis-related genes participate in regulatory processes of cancer. In this study, 538 differentially expressed ferroptosis-related lncRNAs were identified from the The Cancer Genome Atlas database through co-expression method and differential expression analysis. Then, the samples involved were equally and randomly divided into two cohorts for the construction of gene model and accuracy verification. Subsequently, a prediction model containing five ferroptosis-related lncRNAs was constructed by LASSO and Cox regression an"],"journal":["Frontiers in cell and developmental biology"],"pubmed_title":["Development and Validation of Ferroptosis-Related LncRNA Biomarker in Bladder Carcinoma."],"pmcid":["PMC8924052"],"funding_grant_id":["2021T140170"],"pubmed_authors":["Li G","Liu X","Yin H","Chen J","Wang S","Wang Y","Zhang S","Bai Y"],"additional_accession":[]},"is_claimable":false,"name":"Development and Validation of Ferroptosis-Related LncRNA Biomarker in Bladder Carcinoma.","description":"Bladder cancer (BC) is a highly prevalent cancer form of the genitourinary system; however, the effective biomarkers are still ambiguous and deserve deeper investigation. Long non-coding RNA (lncRNA) occupies a prominent position in tumor biology and immunology, and ferroptosis-related genes participate in regulatory processes of cancer. In this study, 538 differentially expressed ferroptosis-related lncRNAs were identified from the The Cancer Genome Atlas database through co-expression method and differential expression analysis. Then, the samples involved were equally and randomly divided into two cohorts for the construction of gene model and accuracy verification. Subsequently, a prediction model containing five ferroptosis-related lncRNAs was constructed by LASSO and Cox regression an","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022","modification":"2025-06-01T00:39:12.325Z","creation":"2025-06-01T00:39:12.325Z"},"accession":"S-EPMC8924052","cross_references":{"pubmed":["35309945"],"doi":["10.3389/fcell.2022.809747"]}}