{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Ritz B"],"funding":["NIEHS NIH HHS","NCI NIH HHS"],"pagination":["111907"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8926017"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["203"],"pubmed_abstract":["<h4>Background</h4>Maternal exposure to traffic-related air pollution during pregnancy has been shown to increase the risk of adverse birth outcomes and childhood disorders. High-resolution metabolomics (HRM) has previously been employed to identify metabolic responses to traffic-related air pollution in adults, including pregnant women. Thus far, no studies have examined metabolic effects of air pollution exposure in utero on neonates.<h4>Methods</h4>We retrieved stored neonatal blood spots for 241 children born in California between 1998 and 2007. These children were randomly selected from all California birth rolls to serve as birth-year matched controls for children with retinoblastoma identified from the California cancer registry for a case control study of childhood cancer. We estim"],"journal":["Environmental research"],"pubmed_title":["Child serum metabolome and traffic-related air pollution exposure in pregnancy."],"pmcid":["PMC8926017"],"funding_grant_id":["R03 CA252788","R21 ES018960","R21 ES019986"],"pubmed_authors":["Wu J","Walker DI","He D","Uppal K","Ritz B","Yan Q","Jones DP","Heck JE"],"additional_accession":[]},"is_claimable":false,"name":"Child serum metabolome and traffic-related air pollution exposure in pregnancy.","description":"<h4>Background</h4>Maternal exposure to traffic-related air pollution during pregnancy has been shown to increase the risk of adverse birth outcomes and childhood disorders. High-resolution metabolomics (HRM) has previously been employed to identify metabolic responses to traffic-related air pollution in adults, including pregnant women. Thus far, no studies have examined metabolic effects of air pollution exposure in utero on neonates.<h4>Methods</h4>We retrieved stored neonatal blood spots for 241 children born in California between 1998 and 2007. These children were randomly selected from all California birth rolls to serve as birth-year matched controls for children with retinoblastoma identified from the California cancer registry for a case control study of childhood cancer. We estim","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Jan","modification":"2025-04-21T15:22:41.082Z","creation":"2025-04-21T15:22:41.082Z"},"accession":"S-EPMC8926017","cross_references":{"pubmed":["34419469"],"doi":["10.1016/j.envres.2021.111907"]}}