{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["37(2)"],"submitter":["Itoh T"],"funding":["Terumo"],"pubmed_abstract":["The purpose of this study was to assess early and late vascular healing in response to bioresorbable-polymer sirolimus-eluting stents (BP-SESs) for the treatment of patients with ST-elevation myocardial infarction (STEMI) and stable coronary artery disease (CAD). A total of 106 patients with STEMI and 101 patients with stable-CAD were enrolled. Optical frequency-domain images were acquired at baseline, at 1- or 3-month follow-up, and at 12-month follow-up. In the STEMI and CAD cohorts, the percentage of uncovered struts (%US) was significantly and remarkably decreased during early two points and at 12-month (the STEMI cohort: 1-month: 18.75 ± 0.78%, 3-month: 10.19 ± 0.77%, 12-month: 1.80 ± 0.72%; p < 0.001, the CAD cohort: 1-month: 9.44 ± 0.78%, 3-month: 7.78 ± 0.78%, 12-month: 1.07 ± 0.73"],"journal":["Cardiovascular intervention and therapeutics"],"pagination":["281-292"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8926965"],"repository":["biostudies-literature"],"pubmed_title":["A serial optical frequency-domain imaging study of early and late vascular responses to bioresorbable-polymer sirolimus-eluting stents for the treatment of acute myocardial infarction and stable coronary artery disease patients: results of the MECHANISM-ULTIMASTER study."],"pmcid":["PMC8926965"],"pubmed_authors":["Hibi K","Kimura T","Kuriyama N","Hayashi T","Morita T","Sakakibara M","Yasaka Y","Shimoda Y","Tsutsui Y","Jinno Y","Masuda N","Soeda T","Okura H","Otsuka Y","MECHANISM-ULTIMASTER study group","Takaya T","Takenaka T","Kikuchi T","Shinke T","Inoue T","Kozuki A","Morino Y","Kaetsu Y","Ishii H","Okamura T","Kadotani M","Itoh T","Okubo M","Abe M","Shite J","Isshiki T","Tsukiyama Y","Tanabe K","Sonoda S","Otake H","Mochizuki M","Kuramitsu S","Ishihara S"],"additional_accession":[]},"is_claimable":false,"name":"A serial optical frequency-domain imaging study of early and late vascular responses to bioresorbable-polymer sirolimus-eluting stents for the treatment of acute myocardial infarction and stable coronary artery disease patients: results of the MECHANISM-ULTIMASTER study.","description":"The purpose of this study was to assess early and late vascular healing in response to bioresorbable-polymer sirolimus-eluting stents (BP-SESs) for the treatment of patients with ST-elevation myocardial infarction (STEMI) and stable coronary artery disease (CAD). A total of 106 patients with STEMI and 101 patients with stable-CAD were enrolled. Optical frequency-domain images were acquired at baseline, at 1- or 3-month follow-up, and at 12-month follow-up. In the STEMI and CAD cohorts, the percentage of uncovered struts (%US) was significantly and remarkably decreased during early two points and at 12-month (the STEMI cohort: 1-month: 18.75 ± 0.78%, 3-month: 10.19 ± 0.77%, 12-month: 1.80 ± 0.72%; p < 0.001, the CAD cohort: 1-month: 9.44 ± 0.78%, 3-month: 7.78 ± 0.78%, 12-month: 1.07 ± 0.73","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Apr","modification":"2025-04-19T09:25:39.33Z","creation":"2024-11-09T10:31:39.891Z"},"accession":"S-EPMC8926965","cross_references":{"pubmed":["33895962"],"doi":["10.1007/s12928-021-00777-4"]}}