{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Di Somma A"],"funding":["PRIN 2017","Ministry of Education, Universities and Research"],"pagination":["1-13"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8929087"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["44(1)"],"pubmed_abstract":["Antibiotics are commonly used to treat pathogenic bacteria, but their prolonged use contributes to the development and spread of drug-resistant microorganisms raising the challenge to find new alternative drugs. Antimicrobial peptides (AMPs) are small/medium molecules ranging 10-60 residues synthesized by all living organisms and playing important roles in the defense systems. These features, together with the inability of microorganisms to develop resistance against the majority of AMPs, suggest that these molecules might represent effective alternatives to classical antibiotics. Because of their high biodiversity, with over one million described species, and their ability to live in hostile environments, insects represent the largest source of these molecules. However, production of inse"],"journal":["Current issues in molecular biology"],"pubmed_title":["Structural and Functional Characterization of a Novel Recombinant Antimicrobial Peptide from <i>Hermetia illucens</i>."],"pmcid":["PMC8929087"],"funding_grant_id":["\"Identification and characterization of novel antitumoral/antimicrobial insect-derived peptides: a multidisciplinary, integrated approach from in silico to in vivo\"","“Identification and characterization of novel antitumoral/antimicrobial insect-derived peptides: a multidisciplinary, integrated approach from in silico to in vivo”","ARS01_00597"],"pubmed_authors":["Di Somma A","Falabella P","Duilio A","Scieuzo C","Cane C","Salvia R","Moretta A"],"additional_accession":[]},"is_claimable":false,"name":"Structural and Functional Characterization of a Novel Recombinant Antimicrobial Peptide from <i>Hermetia illucens</i>.","description":"Antibiotics are commonly used to treat pathogenic bacteria, but their prolonged use contributes to the development and spread of drug-resistant microorganisms raising the challenge to find new alternative drugs. Antimicrobial peptides (AMPs) are small/medium molecules ranging 10-60 residues synthesized by all living organisms and playing important roles in the defense systems. These features, together with the inability of microorganisms to develop resistance against the majority of AMPs, suggest that these molecules might represent effective alternatives to classical antibiotics. Because of their high biodiversity, with over one million described species, and their ability to live in hostile environments, insects represent the largest source of these molecules. However, production of inse","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Dec","modification":"2025-04-04T09:41:03.809Z","creation":"2025-04-04T09:41:03.809Z"},"accession":"S-EPMC8929087","cross_references":{"pubmed":["35723380"],"doi":["10.3390/cimb44010001"]}}