{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Khanal S"],"funding":["NEI NIH HHS","National Eye Institute"],"pagination":["1076-1086"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8929402"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["41(5)"],"pubmed_abstract":["<h4>Purpose</h4>Exposure to narrow-band red light, which stimulates only the long-wavelength sensitive (LWS) cones, slows axial eye growth and produces hyperopia in tree shrews and macaque monkeys. We asked whether exposure to amber light, which also stimulates only the LWS cones but with a greater effective illuminance than red light, has a similar hyperopia-inducing effect in tree shrews.<h4>Methods</h4>Starting at 24 ± 1 days of visual experience, 15 tree shrews (dichromatic mammals closely related to primates) received light treatment through amber filters (BPI 500/550 dyed acrylic) either atop the cage (Filter group, n = 8, 300-400 human lux) or fitted into goggles in front of both eyes (Goggle group, n = 7). Non-cycloplegic refractive error and axial ocular dimensions were measured d"],"journal":["Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)"],"pubmed_title":["Amber light treatment produces hyperopia in tree shrews."],"pmcid":["PMC8929402"],"funding_grant_id":["P30 EY003909","NEI RO1 EY028578","R01 EY028578","P30 EY003039","R21 EY025254","NEI R21 EY025254"],"pubmed_authors":["Khanal S","Norton TT","Gawne TJ"],"additional_accession":[]},"is_claimable":false,"name":"Amber light treatment produces hyperopia in tree shrews.","description":"<h4>Purpose</h4>Exposure to narrow-band red light, which stimulates only the long-wavelength sensitive (LWS) cones, slows axial eye growth and produces hyperopia in tree shrews and macaque monkeys. We asked whether exposure to amber light, which also stimulates only the LWS cones but with a greater effective illuminance than red light, has a similar hyperopia-inducing effect in tree shrews.<h4>Methods</h4>Starting at 24 ± 1 days of visual experience, 15 tree shrews (dichromatic mammals closely related to primates) received light treatment through amber filters (BPI 500/550 dyed acrylic) either atop the cage (Filter group, n = 8, 300-400 human lux) or fitted into goggles in front of both eyes (Goggle group, n = 7). Non-cycloplegic refractive error and axial ocular dimensions were measured d","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Sep","modification":"2025-04-25T17:40:25.773Z","creation":"2025-04-06T05:51:23.541Z"},"accession":"S-EPMC8929402","cross_references":{"pubmed":["34382245"],"doi":["10.1111/opo.12853"]}}