{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["2022"],"submitter":["Zuin M"],"pubmed_abstract":["<h4>Aim</h4>To review and compare the PON-1 arylesterase activity between coronary artery disease (CAD) and non-CAD patients.<h4>Methods</h4>Data were obtained by searching MEDLINE and Scopus for all investigations published between January 1, 2000 and March 1, 2021 comparing PON-1 arylesterase activity between CAD and controls.<h4>Results</h4>Twenty studies, based on 5417 patients, met the inclusion criteria and were included in the analysis. A random effect model revealed that PON-1 arylesterase activity was significantly lower in the CAD group compared to controls (SMD = -0.587, 95%CI = -0.776 to -0.339, <i>p</i> < 0.0001, <i>I</i> <sup>2</sup> = 92.3%). In CAD patients, the PON-1 arylesterase activity was significantly higher among CAD patients without diabetes mellitus (DM) compared t"],"journal":["Disease markers"],"pagination":["4264314"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8930235"],"repository":["biostudies-literature"],"pubmed_title":["Paraoxonase-1 (PON-1) Arylesterase Activity Levels in Patients with Coronary Artery Disease: A Meta-Analysis."],"pmcid":["PMC8930235"],"pubmed_authors":["Cervellati C","Passaro A","Bosi C","D'Amuri A","Marsillach J","Zuin M","Zuliani G","Trentini A","Roncon L","Mackness M"],"additional_accession":[]},"is_claimable":false,"name":"Paraoxonase-1 (PON-1) Arylesterase Activity Levels in Patients with Coronary Artery Disease: A Meta-Analysis.","description":"<h4>Aim</h4>To review and compare the PON-1 arylesterase activity between coronary artery disease (CAD) and non-CAD patients.<h4>Methods</h4>Data were obtained by searching MEDLINE and Scopus for all investigations published between January 1, 2000 and March 1, 2021 comparing PON-1 arylesterase activity between CAD and controls.<h4>Results</h4>Twenty studies, based on 5417 patients, met the inclusion criteria and were included in the analysis. A random effect model revealed that PON-1 arylesterase activity was significantly lower in the CAD group compared to controls (SMD = -0.587, 95%CI = -0.776 to -0.339, <i>p</i> < 0.0001, <i>I</i> <sup>2</sup> = 92.3%). In CAD patients, the PON-1 arylesterase activity was significantly higher among CAD patients without diabetes mellitus (DM) compared t","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022","modification":"2025-04-04T20:23:35.523Z","creation":"2025-04-04T20:23:35.523Z"},"accession":"S-EPMC8930235","cross_references":{"pubmed":["35308142"],"doi":["10.1155/2022/4264314"]}}