biostudies-literatureUnknown1089Mar-Silva AFConsejo Nacional de Ciencia y Tecnología<i>Ophisternoninfernale</i> is one of the 200+ troglobitic fish species worldwide, and one of the two cave-dwelling fishes endemic to the karstic aquifer of the Yucatán Peninsula, Mexico. Because of its elusive nature and the relative inaccessibility of its habitat, there is virtually no genetic information on this enigmatic fish. Herein we report the complete mitochondrial genome of <i>O.infernale</i>, which overall exhibits a configuration comparable to that of other synbranchiforms as well as of more distantly related teleosts. The K_A/K_S ratio indicates that most mtDNA PCGs in synbranchiforms have evolved under strong purifying selection, preventing major structural and functional protein changes. The few instances of PCGs under positive selection might be related ZooKeys1-23https://www.ebi.ac.uk/biostudies/studies/S-EPMC8933388biostudies-literatureThe complete mitochondrial genome of the Mexican-endemic cavefish <i>Ophisternoninfernale</i> (Synbranchiformes, Synbranchidae): insights on patterns of selection and implications for synbranchiform phylogenetics.PMC8933388Diaz-Jaimes PMar-Silva AFArroyave JfalseThe complete mitochondrial genome of the Mexican-endemic cavefish <i>Ophisternoninfernale</i> (Synbranchiformes, Synbranchidae): insights on patterns of selection and implications for synbranchiform phylogenetics.<i>Ophisternoninfernale</i> is one of the 200+ troglobitic fish species worldwide, and one of the two cave-dwelling fishes endemic to the karstic aquifer of the Yucatán Peninsula, Mexico. Because of its elusive nature and the relative inaccessibility of its habitat, there is virtually no genetic information on this enigmatic fish. Herein we report the complete mitochondrial genome of <i>O.infernale</i>, which overall exhibits a configuration comparable to that of other synbranchiforms as well as of more distantly related teleosts. The K_A/K_S ratio indicates that most mtDNA PCGs in synbranchiforms have evolved under strong purifying selection, preventing major structural and functional protein changes. The few instances of PCGs under positive selection might be related 2022-01-01T00:00:00Z20222025-05-18T12:04:44.364Z2025-04-05T20:38:21.693ZS-EPMC89333883558660010.3897/zookeys.1089.78182