biostudies-literatureTan LEuropean Research CouncilStockholms Universitet (Stockholm University)Vetenskapsrådet (Swedish Research Council)Beijing Institute of Technology (BIT)Verband der Chemischen Industrie (Chemical Industry Association)National Natural Science Foundation of China (National Science Foundation of China)1471https://www.ebi.ac.uk/biostudies/studies/S-EPMC8933400biostudies-literatureUnknown13(1)The construction of hierarchically nanoporous composite for high-performance catalytic application is still challenging. In this work, a series of host-in-host ionic porous materials are crafted by encapsulating ionic organic cages into a hyper-crosslinked, oppositely charged porous poly(ionic liquid) (PoPIL) through an ion pair-directed assembly strategy. Specifically, the cationic cage (C-Cage) as the inner host can spatially accommodate a functional Au cluster, forming a [Au⊂C-Cage⁺]⊂PoPIL^- supramolecular composite. This dual-host molecular hierarchy enables a charge-selective substrate sorting effect to the Au clusters, which amplifies their catalytic activity by at least one order of magnitude as compared to Au confined only by C-Cage as the mono-host (Au⊂C-Cage⁺). Moreover, we demonstrate that such dual-host porous system can advantageously immobilize electrostatically repulsive Au⊂C-Cage⁺ and cationic ferrocene co-catalyst (Fer⁺) together into the same microcompartments, and synergistically speed up the enzyme-like tandem reactions by channelling the substrate to the catalytic centers via nanoconfinement.Nature communicationsElectrostatically cooperative host-in-host of metal cluster ⊂ ionic organic cages in nanopores for enhanced catalysis.PMC8933400NAPOLI-639720SU FV-2.1.1-005639720220710082018-05351Dozentenpreis 15126520030293100011181910Tan LZhou JHSun JKYuan JfalseElectrostatically cooperative host-in-host of metal cluster ⊂ ionic organic cages in nanopores for enhanced catalysis.The construction of hierarchically nanoporous composite for high-performance catalytic application is still challenging. In this work, a series of host-in-host ionic porous materials are crafted by encapsulating ionic organic cages into a hyper-crosslinked, oppositely charged porous poly(ionic liquid) (PoPIL) through an ion pair-directed assembly strategy. Specifically, the cationic cage (C-Cage) as the inner host can spatially accommodate a functional Au cluster, forming a [Au⊂C-Cage⁺]⊂PoPIL^- supramolecular composite. This dual-host molecular hierarchy enables a charge-selective substrate sorting effect to the Au clusters, which amplifies their catalytic activity by at least one order of magnitude as compared to Au confined only by C-Cage as the mono-host (Au⊂C-Cage⁺). Moreover, we demonstrate that such dual-host porous system can advantageously immobilize electrostatically repulsive Au⊂C-Cage⁺ and cationic ferrocene co-catalyst (Fer⁺) together into the same microcompartments, and synergistically speed up the enzyme-like tandem reactions by channelling the substrate to the catalytic centers via nanoconfinement.2022-01-01T00:00:00Z2022 Mar2025-05-29T21:53:02.33Z2025-05-29T21:53:02.33ZS-EPMC89334003530446810.1038/s41467-022-29031-y