biostudies-literatureSu PNIBIB NIH HHSNIA NIH HHSNINDS NIH HHSNational Institutes of HealthNIH HHS116-122https://www.ebi.ac.uk/biostudies/studies/S-EPMC8934382biostudies-literatureUnknown88<h4>Purpose</h4>MR Fingerprinting (MRF) Arterial Spin Labeling (ASL) is a non-contrast technique to estimate multiple brain hemodynamic and structural parameters in a single scan. The purpose of this study is to examine the feasibility and initial utility of MRF-ASL in Moyamoya disease.<h4>Methods</h4>MRF-ASL, conventional single-delay ASL, Time-of-flight (TOF) MR angiography, and contrast-based dynamic-susceptibility-contrast (DSC) MRI were prospectively collected from a group of Moyamoya patients in North America (N = 21, 4 men and 17 women). Sixteen healthy subjects (7 men and 9 women) also underwent an MRF-ASL scan. Cerebral blood flow (CBF), bolus arrival time (BAT), and tissue T1 were compared between Moyamoya patients and healthy controls. Perfusion parameters from MRF-ASL were compMagnetic resonance imagingNon-contrast hemodynamic imaging of Moyamoya disease with MR fingerprinting ASL: A feasibility study.PMC8934382R01 AG064792RF1 AG071515AHA16PRE30930003R01 NS106711R01 NS106702S10 OD021648P41 EB031771Qiao YThomas BPSu PHuang JLu HPinho MCLiu PWelch BGfalseNon-contrast hemodynamic imaging of Moyamoya disease with MR fingerprinting ASL: A feasibility study.<h4>Purpose</h4>MR Fingerprinting (MRF) Arterial Spin Labeling (ASL) is a non-contrast technique to estimate multiple brain hemodynamic and structural parameters in a single scan. The purpose of this study is to examine the feasibility and initial utility of MRF-ASL in Moyamoya disease.<h4>Methods</h4>MRF-ASL, conventional single-delay ASL, Time-of-flight (TOF) MR angiography, and contrast-based dynamic-susceptibility-contrast (DSC) MRI were prospectively collected from a group of Moyamoya patients in North America (N = 21, 4 men and 17 women). Sixteen healthy subjects (7 men and 9 women) also underwent an MRF-ASL scan. Cerebral blood flow (CBF), bolus arrival time (BAT), and tissue T1 were compared between Moyamoya patients and healthy controls. Perfusion parameters from MRF-ASL were comp2022-01-01T00:00:00Z2022 May2025-04-27T21:25:48.758Z2025-04-06T19:18:09.239ZS-EPMC89343823518365910.1016/j.mri.2022.02.006