{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["9(2)"],"submitter":["Naghashzadeh F"],"pubmed_abstract":["SARS-CoV-2 vaccines provide a safe solution with a major impact on reducing the spread of the virus and mild side effects. Research has shown rare cases of myocarditis after mRNA vaccines. This study presents a 29-year-old male with chest pain after 48 h of receiving rAd26 and rAd5 vector-based COVID-19 vaccine (Sputnik V vaccine). The electrocardiogram revealed ST-segment elevation. Also, the laboratory screening was remarkable for elevated cardiac Troponin-I level, and leukocytosis; and echocardiography depicted severe left ventricular systolic dysfunction. Overall, endomyocardial biopsy proved lymphocytic myocarditis such that the patient was successfully treated with immunosuppressive and guideline-directed medical treatment."],"journal":["ESC heart failure"],"pagination":["1483-1486"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8934948"],"repository":["biostudies-literature"],"pubmed_title":["Myocarditis following rAd26 and rAd5 vector-based COVID-19 vaccine: case report."],"pmcid":["PMC8934948"],"pubmed_authors":["Naghashzadeh F","Dorudinia A","Marjani M","Kashani BS","Shafaghi S","Mohamadifar A","Noorali S","Naji SA","Amin A"],"additional_accession":[]},"is_claimable":false,"name":"Myocarditis following rAd26 and rAd5 vector-based COVID-19 vaccine: case report.","description":"SARS-CoV-2 vaccines provide a safe solution with a major impact on reducing the spread of the virus and mild side effects. Research has shown rare cases of myocarditis after mRNA vaccines. This study presents a 29-year-old male with chest pain after 48 h of receiving rAd26 and rAd5 vector-based COVID-19 vaccine (Sputnik V vaccine). The electrocardiogram revealed ST-segment elevation. Also, the laboratory screening was remarkable for elevated cardiac Troponin-I level, and leukocytosis; and echocardiography depicted severe left ventricular systolic dysfunction. Overall, endomyocardial biopsy proved lymphocytic myocarditis such that the patient was successfully treated with immunosuppressive and guideline-directed medical treatment.","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Apr","modification":"2025-04-19T13:00:32.984Z","creation":"2025-04-19T13:00:32.984Z"},"accession":"S-EPMC8934948","cross_references":{"pubmed":["35106967"],"doi":["10.1002/ehf2.13821"]}}