{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Certel SJ"],"funding":["Swiss National Science Foundation","National Institutes of Health","NIGMS NIH HHS"],"pagination":["109540"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8940707"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["372"],"pubmed_abstract":["<h4>Background</h4>Throughout the animal kingdom, GABA is the principal inhibitory neurotransmitter of the nervous system. It is essential for maintaining the homeostatic balance between excitation and inhibition required for the brain to operate normally. Identification of GABAergic neurons and their GABA release sites are thus essential for understanding how the brain regulates the excitability of neurons and the activity of neural circuits responsible for numerous aspects of brain function including information processing, locomotion, learning, memory, and synaptic plasticity, among others.<h4>New method</h4>Since the structure and features of GABA synapses are critical to understanding their function within specific neural circuits of interest, here we developed and characterized a con"],"journal":["Journal of neuroscience methods"],"pubmed_title":["A conditional GABAergic synaptic vesicle marker for Drosophila."],"pmcid":["PMC8940707"],"funding_grant_id":["R01 GM115510","179587"],"pubmed_authors":["Certel SJ","Stowers RS","McCabe BD"],"additional_accession":[]},"is_claimable":false,"name":"A conditional GABAergic synaptic vesicle marker for Drosophila.","description":"<h4>Background</h4>Throughout the animal kingdom, GABA is the principal inhibitory neurotransmitter of the nervous system. It is essential for maintaining the homeostatic balance between excitation and inhibition required for the brain to operate normally. Identification of GABAergic neurons and their GABA release sites are thus essential for understanding how the brain regulates the excitability of neurons and the activity of neural circuits responsible for numerous aspects of brain function including information processing, locomotion, learning, memory, and synaptic plasticity, among others.<h4>New method</h4>Since the structure and features of GABA synapses are critical to understanding their function within specific neural circuits of interest, here we developed and characterized a con","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Apr","modification":"2025-04-21T22:59:13.862Z","creation":"2025-04-05T18:58:35.285Z"},"accession":"S-EPMC8940707","cross_references":{"pubmed":["35219770"],"doi":["10.1016/j.jneumeth.2022.109540"]}}