{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Kennett DJ"],"funding":["U.S. Department of Health & Human Services | NIH | National Institute of General Medical Sciences","Howard Hughes Medical Institute","NHGRI NIH HHS","Paul G. Allen Family Foundation","NIGMS NIH HHS"],"pagination":["1530"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8940966"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["13(1)"],"pubmed_abstract":["The genetic prehistory of human populations in Central America is largely unexplored leaving an important gap in our knowledge of the global expansion of humans. We report genome-wide ancient DNA data for a transect of twenty individuals from two Belize rock-shelters dating between 9,600-3,700 calibrated radiocarbon years before present (cal. BP). The oldest individuals (9,600-7,300 cal. BP) descend from an Early Holocene Native American lineage with only distant relatedness to present-day Mesoamericans, including Mayan-speaking populations. After ~5,600 cal. BP a previously unknown human dispersal from the south made a major demographic impact on the region, contributing more than 50% of the ancestry of all later individuals. This new ancestry derived from a source related to present-day "],"journal":["Nature communications"],"pubmed_title":["South-to-north migration preceded the advent of intensive farming in the Maya region."],"pmcid":["PMC8940966"],"funding_grant_id":["n/a","R01 GM100233","R01 HG012287","GM100233"],"pubmed_authors":["Lipson M","Robinson M","Moes E","Mora-Marin D","Edgar HHJ","Lynch P","Ryan TM","Harper TK","Hill EC","Ray EE","Rohland N","Prufer KM","Reich D","Gutierrez SM","Trask WR","Kate EJ","Ramos J","Culleton BJ","Awe JJ","Morris J","O'Donnell L","George RJ","Kennett DJ"],"additional_accession":[]},"is_claimable":false,"name":"South-to-north migration preceded the advent of intensive farming in the Maya region.","description":"The genetic prehistory of human populations in Central America is largely unexplored leaving an important gap in our knowledge of the global expansion of humans. We report genome-wide ancient DNA data for a transect of twenty individuals from two Belize rock-shelters dating between 9,600-3,700 calibrated radiocarbon years before present (cal. BP). The oldest individuals (9,600-7,300 cal. BP) descend from an Early Holocene Native American lineage with only distant relatedness to present-day Mesoamericans, including Mayan-speaking populations. After ~5,600 cal. BP a previously unknown human dispersal from the south made a major demographic impact on the region, contributing more than 50% of the ancestry of all later individuals. This new ancestry derived from a source related to present-day ","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Mar","modification":"2026-03-27T16:40:59.93Z","creation":"2025-04-04T23:16:44.234Z"},"accession":"S-EPMC8940966","cross_references":{"pubmed":["35318319"],"doi":["10.1038/s41467-022-29158-y"]}}