{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["103(2)"],"submitter":["Bhattarai S"],"funding":["South Dakota State University Agricultural Experiment Station","South Dakota State University Center for Biologics Research and Commercialization"],"pubmed_abstract":["Bovine respiratory disease (BRD) is the most significant cause of cattle morbidity and mortality worldwide. This multifactorial disease has a complex aetiology. Dogma posits a primary viral infection followed by secondary bacterial pneumonia. Bovine rhinitis B virus (BRBV) is an established aetiological agent of BRD, but little is known regarding its pathogenesis. Here, a BRD PCR panel identified 18/153 (11.8 %) lung samples and 20/49 (40.8 %) nasal swabs collected from cattle with respiratory signs as positive for BRBV, which was the most prevalent virus in nasal swabs. Primary bovine tracheal epithelial cells were used to isolate BRBV that was phylogenetically related to contemporary sequences from the USA and Mexico and genetically divergent from the previous sole BRBV isolate. To inves"],"journal":["The Journal of general virology"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8941992"],"repository":["biostudies-literature"],"pubmed_title":["Bovine rhinitis B virus is highly prevalent in acute bovine respiratory disease and causes upper respiratory tract infection in calves."],"pmcid":["PMC8941992"],"pubmed_authors":["Kaushik RS","Lin CM","Temeeyasen G","Hause BM","Li F","Bhattarai S","Palinski R"],"additional_accession":[]},"is_claimable":false,"name":"Bovine rhinitis B virus is highly prevalent in acute bovine respiratory disease and causes upper respiratory tract infection in calves.","description":"Bovine respiratory disease (BRD) is the most significant cause of cattle morbidity and mortality worldwide. This multifactorial disease has a complex aetiology. Dogma posits a primary viral infection followed by secondary bacterial pneumonia. Bovine rhinitis B virus (BRBV) is an established aetiological agent of BRD, but little is known regarding its pathogenesis. Here, a BRD PCR panel identified 18/153 (11.8 %) lung samples and 20/49 (40.8 %) nasal swabs collected from cattle with respiratory signs as positive for BRBV, which was the most prevalent virus in nasal swabs. Primary bovine tracheal epithelial cells were used to isolate BRBV that was phylogenetically related to contemporary sequences from the USA and Mexico and genetically divergent from the previous sole BRBV isolate. To inves","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Feb","modification":"2026-07-14T14:50:08.967Z","creation":"2024-11-06T09:10:31.799Z"},"accession":"S-EPMC8941992","cross_references":{"pubmed":["35130139"],"doi":["10.1099/jgv.0.001714"]}}