{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["186(4)"],"submitter":["Kim Y"],"pubmed_abstract":["<h4>Objective</h4>Despite the known benefit of vitamin D in reducing sarcopenia risk in older adults, its effect against muscle loss in the young population is unknown. We aimed to examine the association of serum 25-hydroxy vitamin D [25(OH)D] level and its changes over time with the risk of incident low muscle mass (LMM) in young and middle-aged adults.<h4>Design</h4>This study is a cohort study.<h4>Methods</h4>The study included Korean adults (median age: 36.9 years) without LMM at baseline followed up for a median of 3.9 years (maximum: 7.3 years). LMM was defined as the appendicular skeletal muscle (ASM) mass by body weight (ASM/weight) of 1 s.d. below the sex-specific mean for the young reference group. Cox proportional hazard models were used to estimate hazard ratios (HRs) with 95%"],"journal":["European journal of endocrinology"],"pagination":["477-487"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8942330"],"repository":["biostudies-literature"],"pubmed_title":["Serum 25-hydroxy vitamin D and the risk of low muscle mass in young and middle-aged Korean adults."],"pmcid":["PMC8942330"],"pubmed_authors":["Kwon MJ","Wild SH","Cho IY","Kim Y","Byrne CD","Chang Y","Ryu S"],"additional_accession":[]},"is_claimable":false,"name":"Serum 25-hydroxy vitamin D and the risk of low muscle mass in young and middle-aged Korean adults.","description":"<h4>Objective</h4>Despite the known benefit of vitamin D in reducing sarcopenia risk in older adults, its effect against muscle loss in the young population is unknown. We aimed to examine the association of serum 25-hydroxy vitamin D [25(OH)D] level and its changes over time with the risk of incident low muscle mass (LMM) in young and middle-aged adults.<h4>Design</h4>This study is a cohort study.<h4>Methods</h4>The study included Korean adults (median age: 36.9 years) without LMM at baseline followed up for a median of 3.9 years (maximum: 7.3 years). LMM was defined as the appendicular skeletal muscle (ASM) mass by body weight (ASM/weight) of 1 s.d. below the sex-specific mean for the young reference group. Cox proportional hazard models were used to estimate hazard ratios (HRs) with 95%","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Mar","modification":"2025-04-19T21:47:37.503Z","creation":"2025-04-19T21:47:37.503Z"},"accession":"S-EPMC8942330","cross_references":{"pubmed":["35147511"],"doi":["10.1530/EJE-21-1229"]}}