{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Caballero N"],"funding":["World Health Organization"],"pagination":["150-156"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8942465"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["3"],"pubmed_abstract":["<h4>Objective</h4>The aim of this study was to determine current and previous SARS-COV-2 infection, and describe risk factors associated with seropositivity, among HCWs and hospital staff between June and October of 2020.<h4>Methodology</h4>Data from the day of enrollment for a prospective cohort study were analyzed to determine point prevalence and seroprevalence of SARS-CoV-2 infection in HCWs and hospital staff of a university hospital in Colombia. Respiratory samples were collected to perform RT-PCR tests, along with blood samples to measure SARS-CoV-2 IgM and IgG antibodies. Data on nosocomial and community risk factors for infection were also collected and analyzed.<h4>Findings</h4>420 HCWs and hospital staff members were included. The seroprevalence at baseline was 23.2%, of which 10.7% had only IgM antibodies, 0.7% had IgG, and 11.7% had IgM and IgG. The prevalence of acute SARS-CoV-2 infection was 1.9%. Being a nurse assistant was significantly associated with seropositivity when compared with all other job duties (PR 2.39, 95% CI 1.27-3.65, <i>p</i> = 0.01).<h4>Conclusions</h4>Overall SARS-CoV-2 prevalence was 1.9% and seroprevalence was 23.15%. Nurse assistants, medical doctors or students, and laboratory workers had a higher possibility of being SARS-CoV-2 seropositive."],"journal":["IJID regions"],"pubmed_title":["Prevalence of SARS-CoV-2 infection and SARS-CoV-2-specific antibody detection among healthcare workers and hospital staff of a university hospital in Colombia."],"pmcid":["PMC8942465"],"funding_grant_id":["001"],"pubmed_authors":["Quintero J","Remolina CI","Rojas DP","Vega D","Moreno S","Duran D","Hernandez LJ","Rodriguez-Urrego PA","Nieto MA","Suarez-Zamora DA","Caballero N","Martinez O","Baldion-Elorza AM","Ramirez A","Gomez CP"],"additional_accession":[]},"is_claimable":false,"name":"Prevalence of SARS-CoV-2 infection and SARS-CoV-2-specific antibody detection among healthcare workers and hospital staff of a university hospital in Colombia.","description":"<h4>Objective</h4>The aim of this study was to determine current and previous SARS-COV-2 infection, and describe risk factors associated with seropositivity, among HCWs and hospital staff between June and October of 2020.<h4>Methodology</h4>Data from the day of enrollment for a prospective cohort study were analyzed to determine point prevalence and seroprevalence of SARS-CoV-2 infection in HCWs and hospital staff of a university hospital in Colombia. Respiratory samples were collected to perform RT-PCR tests, along with blood samples to measure SARS-CoV-2 IgM and IgG antibodies. Data on nosocomial and community risk factors for infection were also collected and analyzed.<h4>Findings</h4>420 HCWs and hospital staff members were included. The seroprevalence at baseline was 23.2%, of which 10.7% had only IgM antibodies, 0.7% had IgG, and 11.7% had IgM and IgG. The prevalence of acute SARS-CoV-2 infection was 1.9%. Being a nurse assistant was significantly associated with seropositivity when compared with all other job duties (PR 2.39, 95% CI 1.27-3.65, <i>p</i> = 0.01).<h4>Conclusions</h4>Overall SARS-CoV-2 prevalence was 1.9% and seroprevalence was 23.15%. Nurse assistants, medical doctors or students, and laboratory workers had a higher possibility of being SARS-CoV-2 seropositive.","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Jun","modification":"2025-04-03T21:30:02.104Z","creation":"2025-04-03T21:30:02.104Z"},"accession":"S-EPMC8942465","cross_references":{"pubmed":["35720138"],"doi":["10.1016/j.ijregi.2022.03.013"]}}