biostudies-literatureProbst VNICHD NIH HHSNCATS NIH HHSNIAID NIH HHS277-283https://www.ebi.ac.uk/biostudies/studies/S-EPMC8943843biostudies-literatureUnknown41(4)<h4>Background</h4>The most common clinical manifestation of adenovirus (AdV) infection is acute respiratory illness (ARI). Specific AdV species associated with ARI hospitalizations are not well defined in the Middle East.<h4>Methods</h4>A viral surveillance study was conducted among children <2 years hospitalized in Amman, Jordan, from March 2010 to March 2013. Nasal and throat respiratory specimens were obtained from enrolled children and tested for viruses using a real-time reverse-transcription quantitative polymerase chain reaction. AdV-positive specimens were typed by partial hexon gene sequencing. Demographic and clinical features were compared between AdV detected as single pathogen versus co-detected with other respiratory viruses, and between AdV-B and AdV-C species.<h4>Results</The Pediatric infectious disease journalAdenovirus Infection in Hospitalized Children with Acute Respiratory Infection in Jordan.PMC8943843UL1 TR002243T32 HD060554TL1 TR002244R01 AI085062UL1 TR000445Yanis ASpieker AJChappell JHalasa NBWilliams JVProbst VStewart LSHaddadin ZHamdan LHoward LRahman HKShehabi AGuevara CFaouri SRankin DAKhuri-Bulos NTalj RYepsen EfalseAdenovirus Infection in Hospitalized Children with Acute Respiratory Infection in Jordan.<h4>Background</h4>The most common clinical manifestation of adenovirus (AdV) infection is acute respiratory illness (ARI). Specific AdV species associated with ARI hospitalizations are not well defined in the Middle East.<h4>Methods</h4>A viral surveillance study was conducted among children <2 years hospitalized in Amman, Jordan, from March 2010 to March 2013. Nasal and throat respiratory specimens were obtained from enrolled children and tested for viruses using a real-time reverse-transcription quantitative polymerase chain reaction. AdV-positive specimens were typed by partial hexon gene sequencing. Demographic and clinical features were compared between AdV detected as single pathogen versus co-detected with other respiratory viruses, and between AdV-B and AdV-C species.<h4>Results</2022-01-01T00:00:00Z2022 Apr2026-06-04T04:58:51.537Z2025-02-19T01:13:25.568ZS-EPMC89438433531582210.1097/inf.000000000000342310.1097/INF.0000000000003423