{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["19(1)"],"submitter":["Belyhun Y"],"funding":["German Academic Exchange Service (DAAD) Friends and Sponsors of Leipzig University","Emeritus Prof. Fusao Ota&apos;s Scholarship for Young Ethiopian Researcher, 2010"],"pubmed_abstract":["<h4>Background</h4>Hepatitis B virus (HBV) infection is a particular concern in human immunodeficiency virus (HIV) infected individuals. In Ethiopia, detailed clinical and virological descriptions of HBV prevailing during HIV co-infection and symptomatic liver disease patients are lacking. The aim of this study was to investigate HBV virological characteristics from Ethiopian HBV/HIV co-infected and HBV mono-infected individuals.<h4>Methods</h4>A total of 4105 sera from HIV positive individuals, liver disease patients, and blood donors were screened serologically for HBV. The overlapping polymerase/surface genome region of HBV from 180 infected individuals was extracted, amplified, and sequenced for genotypic analysis.<h4>Results</h4>The HBsAg seroprevalence was detected 43% in liver disea"],"journal":["Virology journal"],"pagination":["53"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8944073"],"repository":["biostudies-literature"],"pubmed_title":["Molecular epidemiology of hepatitis B virus among HIV co-infected and mono-infected cohorts in Northwest Ethiopia."],"pmcid":["PMC8944073"],"pubmed_authors":["Maier M","Liebert UG","Belyhun Y"],"additional_accession":[]},"is_claimable":false,"name":"Molecular epidemiology of hepatitis B virus among HIV co-infected and mono-infected cohorts in Northwest Ethiopia.","description":"<h4>Background</h4>Hepatitis B virus (HBV) infection is a particular concern in human immunodeficiency virus (HIV) infected individuals. In Ethiopia, detailed clinical and virological descriptions of HBV prevailing during HIV co-infection and symptomatic liver disease patients are lacking. The aim of this study was to investigate HBV virological characteristics from Ethiopian HBV/HIV co-infected and HBV mono-infected individuals.<h4>Methods</h4>A total of 4105 sera from HIV positive individuals, liver disease patients, and blood donors were screened serologically for HBV. The overlapping polymerase/surface genome region of HBV from 180 infected individuals was extracted, amplified, and sequenced for genotypic analysis.<h4>Results</h4>The HBsAg seroprevalence was detected 43% in liver disea","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Mar","modification":"2025-04-04T19:30:07.707Z","creation":"2025-04-04T19:30:07.707Z"},"accession":"S-EPMC8944073","cross_references":{"pubmed":["35331278"],"doi":["10.1186/s12985-022-01774-6"]}}