biostudies-literatureUnknown19(1)Belyhun YGerman Academic Exchange Service (DAAD) Friends and Sponsors of Leipzig UniversityEmeritus Prof. Fusao Ota&apos;s Scholarship for Young Ethiopian Researcher, 2010<h4>Background</h4>Hepatitis B virus (HBV) infection is a particular concern in human immunodeficiency virus (HIV) infected individuals. In Ethiopia, detailed clinical and virological descriptions of HBV prevailing during HIV co-infection and symptomatic liver disease patients are lacking. The aim of this study was to investigate HBV virological characteristics from Ethiopian HBV/HIV co-infected and HBV mono-infected individuals.<h4>Methods</h4>A total of 4105 sera from HIV positive individuals, liver disease patients, and blood donors were screened serologically for HBV. The overlapping polymerase/surface genome region of HBV from 180 infected individuals was extracted, amplified, and sequenced for genotypic analysis.<h4>Results</h4>The HBsAg seroprevalence was detected 43% in liver diseaVirology journal53https://www.ebi.ac.uk/biostudies/studies/S-EPMC8944073biostudies-literatureMolecular epidemiology of hepatitis B virus among HIV co-infected and mono-infected cohorts in Northwest Ethiopia.PMC8944073Maier MLiebert UGBelyhun YfalseMolecular epidemiology of hepatitis B virus among HIV co-infected and mono-infected cohorts in Northwest Ethiopia.<h4>Background</h4>Hepatitis B virus (HBV) infection is a particular concern in human immunodeficiency virus (HIV) infected individuals. In Ethiopia, detailed clinical and virological descriptions of HBV prevailing during HIV co-infection and symptomatic liver disease patients are lacking. The aim of this study was to investigate HBV virological characteristics from Ethiopian HBV/HIV co-infected and HBV mono-infected individuals.<h4>Methods</h4>A total of 4105 sera from HIV positive individuals, liver disease patients, and blood donors were screened serologically for HBV. The overlapping polymerase/surface genome region of HBV from 180 infected individuals was extracted, amplified, and sequenced for genotypic analysis.<h4>Results</h4>The HBsAg seroprevalence was detected 43% in liver disea2022-01-01T00:00:00Z2022 Mar2025-04-04T19:30:07.707Z2025-04-04T19:30:07.707ZS-EPMC89440733533127810.1186/s12985-022-01774-6