{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Li S"],"funding":["Science and Technology Program of Hunan Province","Natural Science Foundation of?Hunan Province","China Postdoctoral Science Foundation","National Natural Science Foundation of China","University of South China"],"pagination":["9929-9935"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8945126"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["7(11)"],"pubmed_abstract":["CO-releasing molecule-3 (CORM-3), mainly metal carbonyl compounds, is widely used as experimental tools to deliver CO, a biological \"gasotransmitter\", in mammalian systems. CORM-3 is also proposed as a potential new antimicrobial agent, which kills bacteria effectively and rapidly in vitro and in animal models. Organelle-targeting therapy, as a highly effective therapeutic strategy with little toxic and side effects, has important research significance and development prospects. Therefore, the development of effective methods for detecting and tracking CORM-3 at the subcellular level has important implications. In this paper, an easily available Golgi-targetable fluorescent probe (Golgi-Nap-CORM-3) was proposed for CORM-3 detection. In the probe Golgi-Nap-CORM-3, the phenyl sulfonamide gro"],"journal":["ACS omega"],"pubmed_title":["Golgi-Targeting Fluorescent Probe for Monitoring CO-Releasing Molecule-3 In Vitro and In Vivo."],"pmcid":["PMC8945126"],"funding_grant_id":["2020JJ5033","2020T130184","21904035","2021RC3108","201RGC012"],"pubmed_authors":["Cheng D","Ding Y","Li S","Yang K","Zeng J","He L"],"additional_accession":[]},"is_claimable":false,"name":"Golgi-Targeting Fluorescent Probe for Monitoring CO-Releasing Molecule-3 In Vitro and In Vivo.","description":"CO-releasing molecule-3 (CORM-3), mainly metal carbonyl compounds, is widely used as experimental tools to deliver CO, a biological \"gasotransmitter\", in mammalian systems. CORM-3 is also proposed as a potential new antimicrobial agent, which kills bacteria effectively and rapidly in vitro and in animal models. Organelle-targeting therapy, as a highly effective therapeutic strategy with little toxic and side effects, has important research significance and development prospects. Therefore, the development of effective methods for detecting and tracking CORM-3 at the subcellular level has important implications. In this paper, an easily available Golgi-targetable fluorescent probe (Golgi-Nap-CORM-3) was proposed for CORM-3 detection. In the probe Golgi-Nap-CORM-3, the phenyl sulfonamide gro","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Mar","modification":"2025-04-19T21:48:25.67Z","creation":"2025-04-19T21:48:25.67Z"},"accession":"S-EPMC8945126","cross_references":{"pubmed":["35350336"],"doi":["10.1021/acsomega.2c00422"]}}