{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["9(4)"],"submitter":["Holger DJ"],"pubmed_abstract":["We report our clinical and laboratory experience treating a 50-year-old patient who was critically ill with extensively drug-resistant <i>Acinetobacter baumannii</i> necrotizing pneumonia complicated by empyema in Detroit, Michigan. A precision medicine approach using whole-genome sequencing, susceptibility testing, and synergy analysis guided the selection of rational combination antimicrobial therapy."],"journal":["Open forum infectious diseases"],"pagination":["ofac092"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8946682"],"repository":["biostudies-literature"],"pubmed_title":["Novel Combination Therapy for Extensively Drug-Resistant <i>Acinetobacter baumannii</i> Necrotizing Pneumonia Complicated by Empyema: A Case Report."],"pmcid":["PMC8946682"],"pubmed_authors":["Kunz Coyne AJ","Zhao JJ","Salimnia H","Sandhu A","Rybak MJ","Holger DJ"],"additional_accession":[]},"is_claimable":false,"name":"Novel Combination Therapy for Extensively Drug-Resistant <i>Acinetobacter baumannii</i> Necrotizing Pneumonia Complicated by Empyema: A Case Report.","description":"We report our clinical and laboratory experience treating a 50-year-old patient who was critically ill with extensively drug-resistant <i>Acinetobacter baumannii</i> necrotizing pneumonia complicated by empyema in Detroit, Michigan. A precision medicine approach using whole-genome sequencing, susceptibility testing, and synergy analysis guided the selection of rational combination antimicrobial therapy.","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Apr","modification":"2026-05-31T21:02:36.341Z","creation":"2025-04-04T21:43:17.672Z"},"accession":"S-EPMC8946682","cross_references":{"pubmed":["35350174"],"doi":["10.1093/ofid/ofac092"]}}