{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Scott IU"],"funding":["NEI NIH HHS"],"pagination":["458-464"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8949717"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["140(5)"],"pubmed_abstract":["<h4>Importance</h4>Intravitreal anti-vascular endothelial growth factor (VEGF) injections are commonly used to treat eyes with macular edema secondary to hemiretinal vein occlusion (HRVO) or central retinal vein occlusion (CRVO). Information on whether differences exist in outcomes after anti-VEGF therapy can help guide treatment for each of the different disease types.<h4>Objective</h4>To compare baseline characteristics, treatment burden, and outcomes of macular edema treatment in participants with HRVO with those of participants with CRVO.<h4>Design, setting, and participants</h4>This post hoc outcome analysis from the Study of Comparative Treatments for Retinal Vein Occlusion 2 randomized clinical trial included 362 participants with macular edema caused by HRVO or CRVO treated at 66 U"],"journal":["JAMA ophthalmology"],"pubmed_title":["Baseline Characteristics and Outcomes After Anti-Vascular Endothelial Growth Factor Therapy for Macular Edema in Participants With Hemiretinal Vein Occlusion Compared With Participants With Central Retinal Vein Occlusion: Study of Comparative Treatments for Retinal Vein Occlusion 2 (SCORE2) Report 18."],"pmcid":["PMC8949717"],"funding_grant_id":["U10 EY023521","U10 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anti-vascular endothelial growth factor (VEGF) injections are commonly used to treat eyes with macular edema secondary to hemiretinal vein occlusion (HRVO) or central retinal vein occlusion (CRVO). Information on whether differences exist in outcomes after anti-VEGF therapy can help guide treatment for each of the different disease types.<h4>Objective</h4>To compare baseline characteristics, treatment burden, and outcomes of macular edema treatment in participants with HRVO with those of participants with CRVO.<h4>Design, setting, and participants</h4>This post hoc outcome analysis from the Study of Comparative Treatments for Retinal Vein Occlusion 2 randomized clinical trial included 362 participants with macular edema caused by HRVO or CRVO treated at 66 U","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 May","modification":"2025-04-05T13:11:47.236Z","creation":"2025-04-05T13:11:47.236Z"},"accession":"S-EPMC8949717","cross_references":{"pubmed":["35323843"],"doi":["10.1001/jamaophthalmol.2022.0352"]}}