{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Tanabe RHS"],"funding":["São Paulo Research Foundation"],"pagination":["645"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8950336"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["10(3)"],"pubmed_abstract":["(1) Background: Pathogenic <i>Escherichia coli</i> are divided into two groups: diarrheagenic (DEC) and extraintestinal pathogenic (ExPEC) <i>E. coli</i>. ExPEC causing urinary tract infections (UTIs) are termed uropathogenic <i>E. coli</i> (UPEC) and are the most common cause of UTIs worldwide. (2) Methods: Here, we characterized 112 UPEC in terms of phylogroup, serotype, the presence of virulence factor-encoding genes, and antimicrobial resistance. (3) Results: The majority of the isolates were assigned into the phylogroup B2 (41.07%), and the serogroups O6 (12.5%) and O25 (8.9%) were the most frequent. Five hybrid UPEC (4.5%), with markers from two DEC pathotypes, i.e., atypical enteropathogenic (aEPEC) and enteroaggregative (EAEC) <i>E. coli</i>, were identified, and designated UPEC/aE"],"journal":["Microorganisms"],"pubmed_title":["Characterization of Uropathogenic <i>Escherichia coli</i> Reveals Hybrid Isolates of Uropathogenic and Diarrheagenic (UPEC/DEC) <i>E. coli</i>."],"pmcid":["PMC8950336"],"funding_grant_id":["2018/17353-7 to T.A.T.G. and 2015/26207-6 to R.T.H."],"pubmed_authors":["Dias RCB","Vieira MA","Hernandes RT","Camargo CH","Gomes TAT","Orsi H","Dos Santos LF","Ferreira AM","Tanabe RHS","de Lira DRP","Mondelli AL","Rall VLM"],"additional_accession":[]},"is_claimable":false,"name":"Characterization of Uropathogenic <i>Escherichia coli</i> Reveals Hybrid Isolates of Uropathogenic and Diarrheagenic (UPEC/DEC) <i>E. coli</i>.","description":"(1) Background: Pathogenic <i>Escherichia coli</i> are divided into two groups: diarrheagenic (DEC) and extraintestinal pathogenic (ExPEC) <i>E. coli</i>. ExPEC causing urinary tract infections (UTIs) are termed uropathogenic <i>E. coli</i> (UPEC) and are the most common cause of UTIs worldwide. (2) Methods: Here, we characterized 112 UPEC in terms of phylogroup, serotype, the presence of virulence factor-encoding genes, and antimicrobial resistance. (3) Results: The majority of the isolates were assigned into the phylogroup B2 (41.07%), and the serogroups O6 (12.5%) and O25 (8.9%) were the most frequent. Five hybrid UPEC (4.5%), with markers from two DEC pathotypes, i.e., atypical enteropathogenic (aEPEC) and enteroaggregative (EAEC) <i>E. coli</i>, were identified, and designated UPEC/aE","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Mar","modification":"2025-08-23T03:08:43.595Z","creation":"2025-02-19T02:02:02.295Z"},"accession":"S-EPMC8950336","cross_references":{"pubmed":["35336220"],"doi":["10.3390/microorganisms10030645"]}}