biostudies-literatureTanabe RHSSão Paulo Research Foundation645https://www.ebi.ac.uk/biostudies/studies/S-EPMC8950336biostudies-literatureUnknown10(3)(1) Background: Pathogenic <i>Escherichia coli</i> are divided into two groups: diarrheagenic (DEC) and extraintestinal pathogenic (ExPEC) <i>E. coli</i>. ExPEC causing urinary tract infections (UTIs) are termed uropathogenic <i>E. coli</i> (UPEC) and are the most common cause of UTIs worldwide. (2) Methods: Here, we characterized 112 UPEC in terms of phylogroup, serotype, the presence of virulence factor-encoding genes, and antimicrobial resistance. (3) Results: The majority of the isolates were assigned into the phylogroup B2 (41.07%), and the serogroups O6 (12.5%) and O25 (8.9%) were the most frequent. Five hybrid UPEC (4.5%), with markers from two DEC pathotypes, i.e., atypical enteropathogenic (aEPEC) and enteroaggregative (EAEC) <i>E. coli</i>, were identified, and designated UPEC/aEMicroorganismsCharacterization of Uropathogenic <i>Escherichia coli</i> Reveals Hybrid Isolates of Uropathogenic and Diarrheagenic (UPEC/DEC) <i>E. coli</i>.PMC89503362018/17353-7 to T.A.T.G. and 2015/26207-6 to R.T.H.Dias RCBVieira MAHernandes RTCamargo CHGomes TATOrsi HDos Santos LFFerreira AMTanabe RHSde Lira DRPMondelli ALRall VLMfalseCharacterization of Uropathogenic <i>Escherichia coli</i> Reveals Hybrid Isolates of Uropathogenic and Diarrheagenic (UPEC/DEC) <i>E. coli</i>.(1) Background: Pathogenic <i>Escherichia coli</i> are divided into two groups: diarrheagenic (DEC) and extraintestinal pathogenic (ExPEC) <i>E. coli</i>. ExPEC causing urinary tract infections (UTIs) are termed uropathogenic <i>E. coli</i> (UPEC) and are the most common cause of UTIs worldwide. (2) Methods: Here, we characterized 112 UPEC in terms of phylogroup, serotype, the presence of virulence factor-encoding genes, and antimicrobial resistance. (3) Results: The majority of the isolates were assigned into the phylogroup B2 (41.07%), and the serogroups O6 (12.5%) and O25 (8.9%) were the most frequent. Five hybrid UPEC (4.5%), with markers from two DEC pathotypes, i.e., atypical enteropathogenic (aEPEC) and enteroaggregative (EAEC) <i>E. coli</i>, were identified, and designated UPEC/aE2022-01-01T00:00:00Z2022 Mar2025-08-23T03:08:43.595Z2025-02-19T02:02:02.295ZS-EPMC89503363533622010.3390/microorganisms10030645