{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["10(3)"],"submitter":["Pino A"],"pubmed_abstract":["Bifidobacteria have long been recognized as bacteria with probiotic and therapeutic features. The aim of this work is to characterize the <i>Bifidobacterium asteroides</i> BA15 and BA17 strains, isolated from honeybee gut, to evaluate its safety for human use. An in-depth assessment was carried out on safety properties (antibiotic resistance profiling, β-hemolytic, DNase and gelatinase activities and virulence factor presence) and other properties (antimicrobial activity, auto-aggregation, co-aggregation and hydrophobicity). Based on phenotypic and genotypic characterization, both strains satisfied all the safety requirements. More specifically, genome analysis showed the absence of genes encoding for glycopeptide (<i>vanA</i>, <i>vanB</i>, <i>vanC</i>-1, <i>vanC</i>-2, <i>vanD</i>, <i>vanE</i>, <i>vanG</i>), resistance to tetracycline (<i>tetM</i>, <i>tetL</i> and <i>tetO</i>) and virulence genes (<i>asa1</i>, <i>gelE</i>, <i>cylA</i>, <i>esp</i>, <i>hyl</i>)."],"journal":["Microorganisms"],"pagination":["655"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8950671"],"repository":["biostudies-literature"],"pubmed_title":["Characterization of <i>Bifidobacterium asteroides</i> Isolates."],"pmcid":["PMC8950671"],"pubmed_authors":["Vaccalluzzo A","Miloud H","Amico P","Caggia C","Pino A","Benkaddour B","Russo N","Vaccaro SC","Agolino G","Randazzo CL","Inturri R"],"additional_accession":[]},"is_claimable":false,"name":"Characterization of <i>Bifidobacterium asteroides</i> Isolates.","description":"Bifidobacteria have long been recognized as bacteria with probiotic and therapeutic features. The aim of this work is to characterize the <i>Bifidobacterium asteroides</i> BA15 and BA17 strains, isolated from honeybee gut, to evaluate its safety for human use. An in-depth assessment was carried out on safety properties (antibiotic resistance profiling, β-hemolytic, DNase and gelatinase activities and virulence factor presence) and other properties (antimicrobial activity, auto-aggregation, co-aggregation and hydrophobicity). Based on phenotypic and genotypic characterization, both strains satisfied all the safety requirements. More specifically, genome analysis showed the absence of genes encoding for glycopeptide (<i>vanA</i>, <i>vanB</i>, <i>vanC</i>-1, <i>vanC</i>-2, <i>vanD</i>, <i>vanE</i>, <i>vanG</i>), resistance to tetracycline (<i>tetM</i>, <i>tetL</i> and <i>tetO</i>) and virulence genes (<i>asa1</i>, <i>gelE</i>, <i>cylA</i>, <i>esp</i>, <i>hyl</i>).","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Mar","modification":"2026-04-08T17:39:37.362Z","creation":"2025-04-06T12:09:40.624Z"},"accession":"S-EPMC8950671","cross_references":{"pubmed":["35336230"],"doi":["10.3390/microorganisms10030655"]}}