biostudies-literatureUnknown46Ning P<h4>Background</h4>Diabetes mellitus (DM) is associated with different clinical complications. The aim of this study was to explore the prevalence of RLS in people with diabetes mellitus and compare the risk of restless leg syndrome (RLS) between diabetic and non-diabetic population.<h4>Methods</h4>We searched for studies of RLS prevalence in DM through PubMed, Embase, and Web of Science. Two authors independently completed the literature screening, data extraction, and bias risk assessment of eligible studies. All observational studies that assessed the prevalence or risk of RLS in DM were included, where the diagnosis of RLS was based on the International Restless Legs Syndrome Study Group (IRLSSG). Percentages, odds ratio (OR) with 95% confidence intervals (CI) were used to assess pooleEClinicalMedicine101357https://www.ebi.ac.uk/biostudies/studies/S-EPMC8956955biostudies-literaturePrevalence of restless legs syndrome in people with diabetes mellitus: A pooling analysis of observational studies.PMC8956955Yang XNing PMu XLi TXu YfalsePrevalence of restless legs syndrome in people with diabetes mellitus: A pooling analysis of observational studies.<h4>Background</h4>Diabetes mellitus (DM) is associated with different clinical complications. The aim of this study was to explore the prevalence of RLS in people with diabetes mellitus and compare the risk of restless leg syndrome (RLS) between diabetic and non-diabetic population.<h4>Methods</h4>We searched for studies of RLS prevalence in DM through PubMed, Embase, and Web of Science. Two authors independently completed the literature screening, data extraction, and bias risk assessment of eligible studies. All observational studies that assessed the prevalence or risk of RLS in DM were included, where the diagnosis of RLS was based on the International Restless Legs Syndrome Study Group (IRLSSG). Percentages, odds ratio (OR) with 95% confidence intervals (CI) were used to assess poole2022-01-01T00:00:00Z2022 Apr2025-04-04T07:44:08.564Z2025-04-04T07:44:08.564ZS-EPMC89569553534553210.1016/j.eclinm.2022.101357