{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Adams-Campbell LL"],"funding":["NCATS NIH HHS","National Center on Minority Health and Health Disparities","NIMHD NIH HHS","National Cancer Institute","NCI NIH HHS","national cancer institute"],"pagination":["2063-2069"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8957631"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["9(5)"],"pubmed_abstract":["Background
Allostatic load comprises cardiovascular, metabolic, and inflammatory markers, which is characterized by abdominal obesity, high blood glucose levels, impaired glucose tolerance, dyslipidemia, and hypertension and associated with an increased risk in breast cancer.Methods
The study was a 6-month, 3-arm randomized controlled trial of two moderate-intensity exercise interventions (compared with a control group) among obese, physically inactive, postmenopausal Black women aged 45 to 65 years, who were at increased risk for breast cancer based on the CARE model. Two hundred thirteen participants were randomly assigned to (1) supervised, facility-based aerobic exercise intervention (n = 73), (2) home-based exercise intervention (n = 69), or (3) a wait-listed control g"],"journal":["Journal of racial and ethnic health disparities"],"pubmed_title":["The Effect of a 6-Month Exercise Intervention Trial on Allostatic Load in Black Women at Increased Risk for Breast Cancer: the FIERCE Study."],"pmcid":["PMC8957631"],"funding_grant_id":["P60 MD006920","K07 CA197112-02","UL1 TR001409","1P60MD006920-01","P30 CA051008","K07 CA197112"],"pubmed_authors":["Dash C","Hicks J","Lu J","Taylor T","Adams-Campbell LL"],"additional_accession":[]},"is_claimable":false,"name":"The Effect of a 6-Month Exercise Intervention Trial on Allostatic Load in Black Women at Increased Risk for Breast Cancer: the FIERCE Study.","description":"Background
Allostatic load comprises cardiovascular, metabolic, and inflammatory markers, which is characterized by abdominal obesity, high blood glucose levels, impaired glucose tolerance, dyslipidemia, and hypertension and associated with an increased risk in breast cancer.Methods
The study was a 6-month, 3-arm randomized controlled trial of two moderate-intensity exercise interventions (compared with a control group) among obese, physically inactive, postmenopausal Black women aged 45 to 65 years, who were at increased risk for breast cancer based on the CARE model. Two hundred thirteen participants were randomly assigned to (1) supervised, facility-based aerobic exercise intervention (n = 73), (2) home-based exercise intervention (n = 69), or (3) a wait-listed control g","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Oct","modification":"2025-06-01T12:37:34.35Z","creation":"2024-11-20T18:15:05.521Z"},"accession":"S-EPMC8957631","cross_references":{"pubmed":["34580826"],"doi":["10.1007/s40615-021-01145-x"]}}