biostudies-literatureUnknown6(6)Mensah AA<h4>Background</h4>Reinfection after primary SARS-CoV-2 infection is uncommon in adults, but little is known about the risks, characteristics, severity, or outcomes of reinfection in children. We aimed to assess the risk of SARS-CoV-2 reinfection in children and compare this with the risk in adults, by analysis of national testing data for England.<h4>Methods</h4>In our prospective, national surveillance study to assess reinfection of SARS-CoV-2 in children in England, we used national SARS-CoV-2 testing data to estimate the risk of reinfection at least 90 days after primary infection from Jan 27, 2020, to July, 31, 2021, which encompassed the alpha (B.1.1.7) and delta (B.1.617.2) variant waves in England. Data from children up to age 16 years who met the criteria for reinfection were inclThe Lancet. Child & adolescent health384-392https://www.ebi.ac.uk/biostudies/studies/S-EPMC8959472biostudies-literatureRisk of SARS-CoV-2 reinfections in children: a prospective national surveillance study between January, 2020, and July, 2021, in England.PMC8959472Mensah AACampbell HBukasa ASimmons RLacy JLadhani SNBrown KRamsay MEO'Boyle SStowe JSeghezzo GfalseRisk of SARS-CoV-2 reinfections in children: a prospective national surveillance study between January, 2020, and July, 2021, in England.<h4>Background</h4>Reinfection after primary SARS-CoV-2 infection is uncommon in adults, but little is known about the risks, characteristics, severity, or outcomes of reinfection in children. We aimed to assess the risk of SARS-CoV-2 reinfection in children and compare this with the risk in adults, by analysis of national testing data for England.<h4>Methods</h4>In our prospective, national surveillance study to assess reinfection of SARS-CoV-2 in children in England, we used national SARS-CoV-2 testing data to estimate the risk of reinfection at least 90 days after primary infection from Jan 27, 2020, to July, 31, 2021, which encompassed the alpha (B.1.1.7) and delta (B.1.617.2) variant waves in England. Data from children up to age 16 years who met the criteria for reinfection were incl2022-01-01T00:00:00Z2022 Jun2025-04-04T21:33:52.284Z2025-04-04T21:33:52.284ZS-EPMC89594723535849110.1016/S2352-4642(22)00059-1