{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["40"],"submitter":["Panuccio G"],"pubmed_abstract":["<h4>Introduction</h4>Cardiogenic shock (CS) is a life-threatening condition and mechanical circulatory support (MCS) might exert a relevant impact on its clinical course. Among MCS devices, Impella is very promising. Yet, its usefulness is still debated. We performed a meta-analysis of all studies evaluating the clinical impact of Impella in CS.<h4>Methods</h4>All studies including patients with CS and treated with Impella were included. The primary endpoint was short-term mortality. Secondary endpoints were vascular access complications and major bleeding. Data synthesis was obtained using random-effects metanalysis.<h4>Results</h4>Thirty-three studies and 5204 patients were included. Short-term mortality was 47%. Meta-regression analysis showed that patients age (p = 0.01), higher suppor"],"journal":["International journal of cardiology. Heart & vasculature"],"pagination":["101007"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8961185"],"repository":["biostudies-literature"],"pubmed_title":["Use of Impella device in cardiogenic shock and its clinical outcomes: A systematic review and meta-analysis."],"pmcid":["PMC8961185"],"pubmed_authors":["Panuccio G","Macri LM","De Rosa S","Neri G","Salerno N","Torella D"],"additional_accession":[]},"is_claimable":false,"name":"Use of Impella device in cardiogenic shock and its clinical outcomes: A systematic review and meta-analysis.","description":"<h4>Introduction</h4>Cardiogenic shock (CS) is a life-threatening condition and mechanical circulatory support (MCS) might exert a relevant impact on its clinical course. Among MCS devices, Impella is very promising. Yet, its usefulness is still debated. We performed a meta-analysis of all studies evaluating the clinical impact of Impella in CS.<h4>Methods</h4>All studies including patients with CS and treated with Impella were included. The primary endpoint was short-term mortality. Secondary endpoints were vascular access complications and major bleeding. Data synthesis was obtained using random-effects metanalysis.<h4>Results</h4>Thirty-three studies and 5204 patients were included. Short-term mortality was 47%. Meta-regression analysis showed that patients age (p = 0.01), higher suppor","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Jun","modification":"2025-04-05T15:59:30.626Z","creation":"2025-04-05T15:59:30.626Z"},"accession":"S-EPMC8961185","cross_references":{"pubmed":["35360892"],"doi":["10.1016/j.ijcha.2022.101007"]}}