biostudies-literatureUnknown10Nayak S<h4>Background</h4>Few single center studies from resource-poor settings have reported about the epidemiology, clinical feature and outcome of multisystem inflammatory syndrome in children (MIS-C). However, larger data from multi-center studies on the same is lacking including from Indian setting.<h4>Methods</h4>This retrospective collaborative study constituted of data collected on MIS-C from five tertiary care teaching hospitals from Eastern India. Children ≤ 15 years of age with MIS-C as per the WHO criteria were included. Primary outcome was mortality.<h4>Results</h4>A total of 134 MIS-C cases were included (median age, 84 months; males constituted 66.7%). Fever was a universal finding. Rash was present in 40%, and conjunctivitis in 71% cases. Gastro-intestinal and respiratory symptomsFrontiers in pediatrics834039https://www.ebi.ac.uk/biostudies/studies/S-EPMC8963178biostudies-literatureEastern India Collaboration on Multisystem Inflammatory Syndrome in Children (EICOMISC): A Multicenter Observational Study of 134 Cases.PMC8963178Sitanshu MSrikanthAgarwalla SKMartina MSoumya Ranjan MSubash Chandra Kumar MBijan Kumar NMahapatro SPriyadarshini DGulla KMShovendra Kumar DSatya Brata PRath DEICOMISC Study GroupNayak SPanda PCMishra PPranab Kumar PChandrakant PSatapathy AKBiswal BJena PKJyotiprakash SMahapatra ADas RRfalseEastern India Collaboration on Multisystem Inflammatory Syndrome in Children (EICOMISC): A Multicenter Observational Study of 134 Cases.<h4>Background</h4>Few single center studies from resource-poor settings have reported about the epidemiology, clinical feature and outcome of multisystem inflammatory syndrome in children (MIS-C). However, larger data from multi-center studies on the same is lacking including from Indian setting.<h4>Methods</h4>This retrospective collaborative study constituted of data collected on MIS-C from five tertiary care teaching hospitals from Eastern India. Children ≤ 15 years of age with MIS-C as per the WHO criteria were included. Primary outcome was mortality.<h4>Results</h4>A total of 134 MIS-C cases were included (median age, 84 months; males constituted 66.7%). Fever was a universal finding. Rash was present in 40%, and conjunctivitis in 71% cases. Gastro-intestinal and respiratory symptoms2022-01-01T00:00:00Z20222025-04-22T07:48:05.738Z2025-04-05T22:21:32.289ZS-EPMC89631783537758310.3389/fped.2022.834039