{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["9"],"submitter":["Meng X"],"pubmed_abstract":["<h4>Introduction and objectives</h4>The risk of ventricular arrhythmia and heart failure in patients with hypertrophic obstructive cardiomyopathy (HOCM) is much higher than that in the general population. More and more pieces of evidence showed that HOCM is the leading cause of sudden cardiac death in young people. We reported our experience in a study, comparing surgical myectomy, alcohol septal ablation (ASA), and medical therapy.<h4>Methods</h4>The original cohort included 965 consecutive patients with HOCM. The patients were divided into three groups according to treatment strategies: myectomy group (<i>n</i> = 502), ASA group (<i>n</i> = 138), and medical treatment group (<i>n</i> = 325). The median follow-up duration was 42.99 ± 18.32 months, and the primary endpoints were all-cause "],"journal":["Frontiers in cardiovascular medicine"],"pagination":["755376"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8964041"],"repository":["biostudies-literature"],"pubmed_title":["Hypertrophic Obstructive Cardiomyopathy: Comparison of Outcomes After Myectomy or Alcohol Ablation."],"pmcid":["PMC8964041"],"pubmed_authors":["Zheng J","Liu Y","Zhang K","Gao J","Tang YD","Wang JJ","Meng X","Wang WY","Shao C"],"additional_accession":[]},"is_claimable":false,"name":"Hypertrophic Obstructive Cardiomyopathy: Comparison of Outcomes After Myectomy or Alcohol Ablation.","description":"<h4>Introduction and objectives</h4>The risk of ventricular arrhythmia and heart failure in patients with hypertrophic obstructive cardiomyopathy (HOCM) is much higher than that in the general population. More and more pieces of evidence showed that HOCM is the leading cause of sudden cardiac death in young people. We reported our experience in a study, comparing surgical myectomy, alcohol septal ablation (ASA), and medical therapy.<h4>Methods</h4>The original cohort included 965 consecutive patients with HOCM. The patients were divided into three groups according to treatment strategies: myectomy group (<i>n</i> = 502), ASA group (<i>n</i> = 138), and medical treatment group (<i>n</i> = 325). The median follow-up duration was 42.99 ± 18.32 months, and the primary endpoints were all-cause ","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022","modification":"2025-05-18T12:06:48.886Z","creation":"2025-05-18T12:06:48.886Z"},"accession":"S-EPMC8964041","cross_references":{"pubmed":["35360040"],"doi":["10.3389/fcvm.2022.755376"]}}