{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["9(2)"],"submitter":["Yaghi NK"],"pubmed_abstract":["<h4>Background</h4>There is growing evidence supporting the need for a short time delay before starting radiotherapy (RT) treatment postsurgery for most optimal responses. The timing of RT initiation and effects on outcomes have been evaluated in a variety of malignancies, but the relationship remains to be well established for brain metastasis.<h4>Methods</h4>Retrospective study of 176 patients (aged 18-89 years) with brain metastases at a single institution (March 2009 to August 2018) who received RT following surgical resection. Time interval (≤22 and >22 days) from surgical resection to initiation of RT and any potential impact on patient outcomes were assessed.<h4>Results</h4>Patients who underwent RT >22 days after surgical resection had a decreased risk for all-cause mortality of 47"],"journal":["Neuro-oncology practice"],"pagination":["133-141"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8965066"],"repository":["biostudies-literature"],"pubmed_title":["Optimal timing of radiotherapy following brain metastases surgery."],"pmcid":["PMC8965066"],"pubmed_authors":["Radu S","Bowden SG","Nugent JG","Han SJ","Mazur-Hart DJ","Yaghi NK","Pang BW","Murphy B"],"additional_accession":[]},"is_claimable":false,"name":"Optimal timing of radiotherapy following brain metastases surgery.","description":"<h4>Background</h4>There is growing evidence supporting the need for a short time delay before starting radiotherapy (RT) treatment postsurgery for most optimal responses. The timing of RT initiation and effects on outcomes have been evaluated in a variety of malignancies, but the relationship remains to be well established for brain metastasis.<h4>Methods</h4>Retrospective study of 176 patients (aged 18-89 years) with brain metastases at a single institution (March 2009 to August 2018) who received RT following surgical resection. Time interval (≤22 and >22 days) from surgical resection to initiation of RT and any potential impact on patient outcomes were assessed.<h4>Results</h4>Patients who underwent RT >22 days after surgical resection had a decreased risk for all-cause mortality of 47","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Apr","modification":"2025-04-06T19:15:49.698Z","creation":"2025-04-06T19:15:49.698Z"},"accession":"S-EPMC8965066","cross_references":{"pubmed":["35371524"],"doi":["10.1093/nop/npac007"]}}