biostudies-literatureUnknown36(2)Williams M<h4>Background</h4>Infection with Bartonella species is common in cats but reported effects of bacteremia on laboratory variables differ.<h4>Objectives</h4>Evaluate for associations between Bartonella bacteremia and CBC and serum biochemical changes in sick and healthy cats throughout the United States.<h4>Animals</h4>A total of 3964 client-owned cats.<h4>Methods</h4>Retrospective cohort study using submissions to a commercial laboratory between 2011 and 2017. Serum biochemistry and CBC abnormalities (categorized as above or below reference intervals), age, and location (high- or low-risk state for Ctenocephalides felis) in presumed healthy and sick cats were evaluated for associations with presence of Bartonella spp. DNA, detected by PCR. Univariate and multivariable logistic regression aJournal of veterinary internal medicine532-540https://www.ebi.ac.uk/biostudies/studies/S-EPMC8965275biostudies-literatureAssociations between presence of Bartonella species deoxyribonucleic acid and complete blood cell count and serum biochemical changes in client-owned cats.PMC8965275Williams MBraff JRao SBuch JSChandrashekar RLappin MRfalseAssociations between presence of Bartonella species deoxyribonucleic acid and complete blood cell count and serum biochemical changes in client-owned cats.<h4>Background</h4>Infection with Bartonella species is common in cats but reported effects of bacteremia on laboratory variables differ.<h4>Objectives</h4>Evaluate for associations between Bartonella bacteremia and CBC and serum biochemical changes in sick and healthy cats throughout the United States.<h4>Animals</h4>A total of 3964 client-owned cats.<h4>Methods</h4>Retrospective cohort study using submissions to a commercial laboratory between 2011 and 2017. Serum biochemistry and CBC abnormalities (categorized as above or below reference intervals), age, and location (high- or low-risk state for Ctenocephalides felis) in presumed healthy and sick cats were evaluated for associations with presence of Bartonella spp. DNA, detected by PCR. Univariate and multivariable logistic regression a2022-01-01T00:00:00Z2022 Mar2026-06-18T08:50:30.783Z2025-04-04T12:57:21.781ZS-EPMC89652753513268510.1111/jvim.16376