biostudies-literatureUnknown9Zhang Y<h4>Objective</h4>We sought to conduct a systematic review and meta-analysis of clinical adverse events in patients undergoing transcatheter aortic valve replacement (TAVR) with bicuspid aortic valve (BAV) vs. tricuspid aortic valve (TAV) anatomy and the efficacy of balloon-expandable (BE) vs. self-expanding (SE) valves in the BAV population. Comparisons aforementioned will be made stratified into early- and new-generation devices. Differences of prosthetic geometry on CT between patients with BAV and TAV were presented. In addition, BAV morphological presentations in included studies were summarized.<h4>Method</h4>Observational studies and a randomized controlled trial of patients with BAV undergoing TAVR were included according to the Preferred Reporting Items for Systematic Reviews and Frontiers in cardiovascular medicine794850https://www.ebi.ac.uk/biostudies/studies/S-EPMC8965870biostudies-literaturePatients With Bicuspid Aortic Stenosis Undergoing Transcatheter Aortic Valve Replacement: A Systematic Review and Meta-Analysis.PMC8965870Peng YHe JJZhu ZKLiu QWei XTang HMeng WHuang FYOu YWang XYao YJZhao ZGBao YChen MYang HRFeng YLi YMChen FLi QLi YJZhou XLiao YBLi XHe SXiong TYZheng MXWei JFZhang YZhou WXfalsePatients With Bicuspid Aortic Stenosis Undergoing Transcatheter Aortic Valve Replacement: A Systematic Review and Meta-Analysis.<h4>Objective</h4>We sought to conduct a systematic review and meta-analysis of clinical adverse events in patients undergoing transcatheter aortic valve replacement (TAVR) with bicuspid aortic valve (BAV) vs. tricuspid aortic valve (TAV) anatomy and the efficacy of balloon-expandable (BE) vs. self-expanding (SE) valves in the BAV population. Comparisons aforementioned will be made stratified into early- and new-generation devices. Differences of prosthetic geometry on CT between patients with BAV and TAV were presented. In addition, BAV morphological presentations in included studies were summarized.<h4>Method</h4>Observational studies and a randomized controlled trial of patients with BAV undergoing TAVR were included according to the Preferred Reporting Items for Systematic Reviews and 2022-01-01T00:00:00Z20222026-05-31T06:03:19.462Z2025-02-19T01:55:24.746ZS-EPMC89658703536935710.3389/fcvm.2022.794850