{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Wen P"],"funding":["National Natural Science Foundation of China"],"pagination":["e0266266"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8967017"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["17(3)"],"pubmed_abstract":["The circadian rhythm affects the biological evolution and operating mechanisms of organisms. The impact of light on the circadian rhythm is a significant concern for both biology and human well-being. However, the relation between different wavelengths, irradiances, and circadian rhythm is unknown. In this study, we compared the effects of four different monochromatic light-emitting diode (LED) light and two different irradiances on the circadian rhythm of a wild-type Neurospora crassa. The results demonstrated that the circadian rhythm of Neurospora crassa can be modulated by violet (λp = 393 nm), blue (λp = 462 nm), and green (λp = 521 nm) light, regardless of the irradiances, in the visible region. Unexpectedly, for the yellow light (λp = 591 nm), the 2 W/m2 light had a more significant impact on circadian rhythm modulation than the 0.04 W/m2 light had. Considering the highest energy of yellow light (2.25 eV) is lower than the High Occupied Molecular Orbital (HOMO)-Lowest Unoccupied Molecular Orbital (LUMO) gap of WC-1 (2.43 eV). We speculate that there may be other potential photoreceptors that are involved in circadian rhythm modulation. The HOMO-LOMO gaps of these proteins are greater than 1.98 eV and less than 2.25 eV. These results provide a strong foundation for a deeper understanding of the impact of different light on the circadian rhythm and also shed light on the identification of new circadian rhythm modulation photoreceptors."],"journal":["PloS one"],"pubmed_title":["Wavelengths and irradiances modulate the circadian rhythm of Neurospora crassa."],"pmcid":["PMC8967017"],"funding_grant_id":["61874004"],"pubmed_authors":["Khan MSA","Lei M","Hu X","Chen W","Wen P","Tan F"],"additional_accession":[]},"is_claimable":false,"name":"Wavelengths and irradiances modulate the circadian rhythm of Neurospora crassa.","description":"The circadian rhythm affects the biological evolution and operating mechanisms of organisms. The impact of light on the circadian rhythm is a significant concern for both biology and human well-being. However, the relation between different wavelengths, irradiances, and circadian rhythm is unknown. In this study, we compared the effects of four different monochromatic light-emitting diode (LED) light and two different irradiances on the circadian rhythm of a wild-type Neurospora crassa. The results demonstrated that the circadian rhythm of Neurospora crassa can be modulated by violet (λp = 393 nm), blue (λp = 462 nm), and green (λp = 521 nm) light, regardless of the irradiances, in the visible region. Unexpectedly, for the yellow light (λp = 591 nm), the 2 W/m2 light had a more significant impact on circadian rhythm modulation than the 0.04 W/m2 light had. Considering the highest energy of yellow light (2.25 eV) is lower than the High Occupied Molecular Orbital (HOMO)-Lowest Unoccupied Molecular Orbital (LUMO) gap of WC-1 (2.43 eV). We speculate that there may be other potential photoreceptors that are involved in circadian rhythm modulation. The HOMO-LOMO gaps of these proteins are greater than 1.98 eV and less than 2.25 eV. These results provide a strong foundation for a deeper understanding of the impact of different light on the circadian rhythm and also shed light on the identification of new circadian rhythm modulation photoreceptors.","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022","modification":"2025-04-04T12:57:51.312Z","creation":"2025-04-04T12:57:51.312Z"},"accession":"S-EPMC8967017","cross_references":{"pubmed":["35353854"],"doi":["10.1371/journal.pone.0266266"]}}