biostudies-literatureUnknown35Khedjat KThe association between blood transfusion and the occurrence of <i>de novo</i> HLA donor specific antibodies (DSA) after kidney transplantation remains controversial. In this single-center observational study, we examined the association between early blood transfusion, i.e. before 1-month post-transplantation, and the risk of DSA occurrence, using Luminex based-methods. In total, 1,424 patients with a minimum of 1-month follow-up were evaluated between January 2007 and December 2018. During a median time of follow-up of 4.52 years, we observed 258 recipients who had at least one blood transfusion during the first month post-transplantation. At baseline, recipients in the transfused group were significant older, more sensitized against HLA class I and class II antibodies and had a higher 1Transplant international : official journal of the European Society for Organ Transplantation10279https://www.ebi.ac.uk/biostudies/studies/S-EPMC8971186biostudies-literaturePost-Transplantation Early Blood Transfusion and Kidney Allograft Outcomes: A Single-Center Observational Study.PMC8971186Frimat MKhedjat KGibier JBTop IMaanaoui MLenain RLabalette MVan Triempont MProvot FHazzan MBaes DHamroun ALopez BfalsePost-Transplantation Early Blood Transfusion and Kidney Allograft Outcomes: A Single-Center Observational Study.The association between blood transfusion and the occurrence of <i>de novo</i> HLA donor specific antibodies (DSA) after kidney transplantation remains controversial. In this single-center observational study, we examined the association between early blood transfusion, i.e. before 1-month post-transplantation, and the risk of DSA occurrence, using Luminex based-methods. In total, 1,424 patients with a minimum of 1-month follow-up were evaluated between January 2007 and December 2018. During a median time of follow-up of 4.52 years, we observed 258 recipients who had at least one blood transfusion during the first month post-transplantation. At baseline, recipients in the transfused group were significant older, more sensitized against HLA class I and class II antibodies and had a higher 12022-01-01T00:00:00Z20222025-04-26T15:15:43.366Z2025-04-06T14:51:13.606ZS-EPMC89711863536863710.3389/ti.2022.10279