{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["13"],"submitter":["Sanz MB"],"pubmed_abstract":["Extraintestinal pathogenic <i>Escherichia coli</i> (ExPEC) causes infections outside the intestine. Particular ExPEC clones, such as clonal complex (CC)/sequence type (ST)131, have been known to sequentially accumulate antimicrobial resistance that starts with chromosomal mutations against fluoroquinolones, followed with the acquisition of <i>bla</i> <sub>CTX-M-15</sub> and, more recently, carbapenemases. Here we aimed to investigate the distribution of global epidemic clones of carbapenemase-producing ExPEC from Argentina in representative clinical isolates recovered between July 2008 and March 2017. Carbapenemase-producing ExPEC (<i>n</i> = 160) were referred to the Argentinean reference laboratory. Of these, 71 were selected for genome sequencing. Phenotypic and microbiological studies "],"journal":["Frontiers in microbiology"],"pagination":["830209"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8971848"],"repository":["biostudies-literature"],"pubmed_title":["Carbapenemase-Producing Extraintestinal Pathogenic <i>Escherichia coli</i> From Argentina: Clonal Diversity and Predominance of Hyperepidemic Clones CC10 and CC131."],"pmcid":["PMC8971848"],"pubmed_authors":["Rocallo M","Gral H","Tula C","Piersigulli A","Sujemecki A","Romeo AM","Cerda N","Gonzalez L","Pidone JC","Gerardo M","Santojanni H","Alfonodo C","Sauer H","Flabiani M","Aleman H","Manganello S","Visus MA","Vacaflor L","Giudice N","Errecalde L","Bottinelli L","Campos J","Lucero C","de Paulis A","Bardi L","Nunez MR","Archuby D","Faccone D","Rapoport M","Bartoli MZ","Poklepovich T","Corso A","Rosato AE","Veliz O","Togneri A","Sanz MB","Carbapenemases-ExPEC Group","Andres P","Reynaldi M","Rodriguez A","Naval H","de Agudos HG","Biondi E","Van der Ploeg C","Di Bella A","Vilaro M","Gomez SA","Pasteran F","Ortiz S","Carol Rey M","Littvik A","Zarate S","Heller H","Roge A","Tuduri E","Baudaz B","De Belder D","de Mendieta JM","Saavedra MO","Badi M","Marinansky AL","Bongiovanni ME"],"additional_accession":[]},"is_claimable":false,"name":"Carbapenemase-Producing Extraintestinal Pathogenic <i>Escherichia coli</i> From Argentina: Clonal Diversity and Predominance of Hyperepidemic Clones CC10 and CC131.","description":"Extraintestinal pathogenic <i>Escherichia coli</i> (ExPEC) causes infections outside the intestine. Particular ExPEC clones, such as clonal complex (CC)/sequence type (ST)131, have been known to sequentially accumulate antimicrobial resistance that starts with chromosomal mutations against fluoroquinolones, followed with the acquisition of <i>bla</i> <sub>CTX-M-15</sub> and, more recently, carbapenemases. Here we aimed to investigate the distribution of global epidemic clones of carbapenemase-producing ExPEC from Argentina in representative clinical isolates recovered between July 2008 and March 2017. Carbapenemase-producing ExPEC (<i>n</i> = 160) were referred to the Argentinean reference laboratory. Of these, 71 were selected for genome sequencing. Phenotypic and microbiological studies ","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022","modification":"2026-04-08T18:16:25.775Z","creation":"2025-02-19T04:22:50.454Z"},"accession":"S-EPMC8971848","cross_references":{"pubmed":["35369469"],"doi":["10.3389/fmicb.2022.830209"]}}