biostudies-literatureUnknown8(5)Hallet J<h4>Importance</h4>Nonfatal self-injury (NFSI) is a patient-centered manifestation of severe distress occurring in 3 out of 1000 patients after cancer diagnosis. How to identify patients at risk for NFSI remains unknown.<h4>Objective</h4>To examine the associations between patient-reported outcome measures and subsequent NFSI in patients with cancer.<h4>Design, setting, and participants</h4>This population-based matched case-control study included adults with a new cancer diagnosis reporting an Edmonton Symptom Assessment System (ESAS) score within 36 months of diagnosis in Ontario, Canada, 2007 to 2019. Data analysis was performed January 2007 to December 2019.<h4>Main outcomes and measures</h4>Cases included patients with NFSI, and controls were patients without NFSI. Cases and controls JAMA oncologye220203https://www.ebi.ac.uk/biostudies/studies/S-EPMC8972147biostudies-literatureAssociation of Patient-Reported Outcomes With Subsequent Nonfatal Self-injury After a New Cancer Diagnosis.PMC8972147Deleemans JEskander AEllis JHong KHallet JHaas BSutradhar RFergus KCoburn NGLook-Hong NVigod SNEnhanced Supportive Psycho-oncology Canadian Care (ESPOC) GroupChan WCIsenberg-Grzeda ENoel CWMahar ALBolton JMason SGoltib Conn LEarle CfalseAssociation of Patient-Reported Outcomes With Subsequent Nonfatal Self-injury After a New Cancer Diagnosis.<h4>Importance</h4>Nonfatal self-injury (NFSI) is a patient-centered manifestation of severe distress occurring in 3 out of 1000 patients after cancer diagnosis. How to identify patients at risk for NFSI remains unknown.<h4>Objective</h4>To examine the associations between patient-reported outcome measures and subsequent NFSI in patients with cancer.<h4>Design, setting, and participants</h4>This population-based matched case-control study included adults with a new cancer diagnosis reporting an Edmonton Symptom Assessment System (ESAS) score within 36 months of diagnosis in Ontario, Canada, 2007 to 2019. Data analysis was performed January 2007 to December 2019.<h4>Main outcomes and measures</h4>Cases included patients with NFSI, and controls were patients without NFSI. Cases and controls 2022-01-01T00:00:00Z2022 May2025-04-21T22:35:56.479Z2024-11-14T09:54:06.178ZS-EPMC89721473535741910.1001/jamaoncol.2022.0203