biostudies-literatureGlynn NWNIA NIH HHSNational Institutes of HealthNational Institute on Aging837-841https://www.ebi.ac.uk/biostudies/studies/S-EPMC8974332biostudies-literatureUnknown77(4)<h4>Background</h4>Perceived physical fatigability is highly prevalent in older adults and associated with mobility decline and other health consequences. We examined the prognostic value of perceived physical fatigability as an independent predictor of risk of death among older adults.<h4>Methods</h4>Participants (N = 2 906), mean age 73.5 [SD, 10.4] years, 54.2% women, 99.7% white enrolled in the Long Life Family Study, were assessed at Visit 2 (2014-2017) with 2.7 [SD, 1.0] years follow-up. The Pittsburgh Fatigability Scale (PFS), a 10-item, self-administered validated questionnaire (score range 0-50, higher = greater fatigability) measured perceived physical fatigability at Visit 2. Deaths post-Visit 2 through December 31, 2019 were identified by family members notifying field centers,The journals of gerontology. Series A, Biological sciences and medical sciencesPerceived Physical Fatigability Predicts All-Cause Mortality in Older Adults.PMC8974332K01 AG057798U19 AG063893U01 AG023755U01 AG023744U01 AG023712U01 AG023749P30 AG024827U01 AG023746P01 AG08761Christensen KGmelin TAndersen SLFeitosa MFNewman ABGlynn NWQiao YSWojczynski MKCosentino SRenner SWBoudreau RMfalsePerceived Physical Fatigability Predicts All-Cause Mortality in Older Adults.<h4>Background</h4>Perceived physical fatigability is highly prevalent in older adults and associated with mobility decline and other health consequences. We examined the prognostic value of perceived physical fatigability as an independent predictor of risk of death among older adults.<h4>Methods</h4>Participants (N = 2 906), mean age 73.5 [SD, 10.4] years, 54.2% women, 99.7% white enrolled in the Long Life Family Study, were assessed at Visit 2 (2014-2017) with 2.7 [SD, 1.0] years follow-up. The Pittsburgh Fatigability Scale (PFS), a 10-item, self-administered validated questionnaire (score range 0-50, higher = greater fatigability) measured perceived physical fatigability at Visit 2. Deaths post-Visit 2 through December 31, 2019 were identified by family members notifying field centers,2022-01-01T00:00:00Z2022 Apr2026-03-27T15:18:01.996Z2025-08-23T03:09:06.155ZS-EPMC89743323490811810.1093/gerona/glab374