{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Reif LK"],"funding":["NCATS NIH HHS","Flora Family Foundation","FIC NIH HHS","NIAID NIH HHS","Fogarty International Center","Camela Basin Family Foundation","Division of Intramural Research, National Institute of Allergy and Infectious Diseases","MAC AIDS Foundation"],"pagination":["409-420"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8976702"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["34(4)"],"pubmed_abstract":["HIV viral load (VL) monitoring can reinforce antiretroviral therapy (ART) adherence. Standard VL testing requires high laboratory capacity and coordination between clinic and laboratory which can delay results. A randomized trial comparing point-of-care (POC) VL testing to standard VL testing among 150 adolescents and young adults, ages 10-24 years, living with HIV in Haiti determined if POC VL testing could return faster results and improve ART adherence and viral suppression. Participants received a POC VL test with same-day result (POC arm) or a standard VL test with result given 1 month later (SOC arm). POC arm participants were more likely to receive a test result within 6 weeks than SOC arm participants (94.7% vs. 80.1%; p1000 copies/ml and low self-reported ART adherence was stronger in the POC arm (OR: 6.57; 95%CI: 2.12-25.21) than the SOC arm (OR: 2.62; 95%CI: 0.97-7.44) suggesting more accurate self-report in the POC arm. POC VL testing was effectively implemented in this low-resource setting with faster results and is a pragmatic intervention that may enable clinicians to identify those with high VL to provide enhanced counseling or regimen changes sooner.<b>Trial registration:</b> ClinicalTrials.gov identifier: NCT03288246."],"journal":["AIDS care"],"pubmed_title":["Point-of-care viral load testing among adolescents and young adults living with HIV in Haiti: a randomized control trial."],"pmcid":["PMC8976702"],"funding_grant_id":["D43 TW10062","UL1 TR002384","D43 TW011295","U01 AI069421","UM1 AI069421","K24 AI098627"],"pubmed_authors":["Reif LK","Kuhn L","Belizaire ME","Arpadi SM","Seo G","Rouzier V","Elul B","McNairy ML","Severe P","Pape JW","Fitzgerald DW","Joseph B","Apollon S","Abrams EJ","Bajo Joseph JM"],"additional_accession":[]},"is_claimable":false,"name":"Point-of-care viral load testing among adolescents and young adults living with HIV in Haiti: a randomized control trial.","description":"HIV viral load (VL) monitoring can reinforce antiretroviral therapy (ART) adherence. Standard VL testing requires high laboratory capacity and coordination between clinic and laboratory which can delay results. A randomized trial comparing point-of-care (POC) VL testing to standard VL testing among 150 adolescents and young adults, ages 10-24 years, living with HIV in Haiti determined if POC VL testing could return faster results and improve ART adherence and viral suppression. Participants received a POC VL test with same-day result (POC arm) or a standard VL test with result given 1 month later (SOC arm). POC arm participants were more likely to receive a test result within 6 weeks than SOC arm participants (94.7% vs. 80.1%; p1000 copies/ml and low self-reported ART adherence was stronger in the POC arm (OR: 6.57; 95%CI: 2.12-25.21) than the SOC arm (OR: 2.62; 95%CI: 0.97-7.44) suggesting more accurate self-report in the POC arm. POC VL testing was effectively implemented in this low-resource setting with faster results and is a pragmatic intervention that may enable clinicians to identify those with high VL to provide enhanced counseling or regimen changes sooner.<b>Trial registration:</b> ClinicalTrials.gov identifier: NCT03288246.","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Apr","modification":"2026-05-09T13:44:57.706Z","creation":"2025-04-07T03:20:28.714Z"},"accession":"S-EPMC8976702","cross_references":{"pubmed":["34612092"],"doi":["10.1080/09540121.2021.1981816"]}}