{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["63(3)"],"submitter":["Lal B"],"pubmed_abstract":["<h4>Purpose</h4>To evaluate changes in the retinal microvasculature of young adults over 24 hours using optical coherence tomography angiography (OCT-A).<h4>Methods</h4>Participants (n = 44, mean age 23.2 ± 4.1 years, 24 myopes and 20 nonmyopes) with normal ophthalmological findings were recruited. Two macular OCT-A and OCT scans, systemic blood pressure, intraocular pressure (IOP), and biometry measurements were taken every four hours over 24 hours. Superficial and deep retinal layer en face images were analyzed to extract magnification-corrected vascular indexes using image analysis including foveal avascular zone metrics, vessel density, and perfusion density for the foveal, parafoveal, and perifoveal zones.<h4>Results</h4>Significant diurnal variations (P < 0.001) were observed in the "],"journal":["Investigative ophthalmology & visual science"],"pagination":["25"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8976927"],"repository":["biostudies-literature"],"pubmed_title":["Changes in Retinal Optical Coherence Tomography Angiography Indexes Over 24 Hours."],"pmcid":["PMC8976927"],"pubmed_authors":["Lal B","Read SA","Tran B","Fiedler JT","Ho S","Carkeet A","Tang D","Van Bui C","Alonso-Caneiro D"],"additional_accession":[]},"is_claimable":false,"name":"Changes in Retinal Optical Coherence Tomography Angiography Indexes Over 24 Hours.","description":"<h4>Purpose</h4>To evaluate changes in the retinal microvasculature of young adults over 24 hours using optical coherence tomography angiography (OCT-A).<h4>Methods</h4>Participants (n = 44, mean age 23.2 ± 4.1 years, 24 myopes and 20 nonmyopes) with normal ophthalmological findings were recruited. Two macular OCT-A and OCT scans, systemic blood pressure, intraocular pressure (IOP), and biometry measurements were taken every four hours over 24 hours. Superficial and deep retinal layer en face images were analyzed to extract magnification-corrected vascular indexes using image analysis including foveal avascular zone metrics, vessel density, and perfusion density for the foveal, parafoveal, and perifoveal zones.<h4>Results</h4>Significant diurnal variations (P < 0.001) were observed in the ","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Mar","modification":"2025-04-04T07:35:14.68Z","creation":"2025-04-04T07:35:14.68Z"},"accession":"S-EPMC8976927","cross_references":{"pubmed":["35348589"],"doi":["10.1167/iovs.63.3.25"]}}