biostudies-literatureHsieh CTMinistry of Science and Technology, Taiwane054638https://www.ebi.ac.uk/biostudies/studies/S-EPMC8977805biostudies-literatureUnknown12(4)<h4>Objectives</h4>Although several studies have investigated the association between fibrinogen level and the risk of cardiovascular disease (CVD), few studies have been conducted in Asia.<h4>Setting</h4>We conducted a community-based prospective cohort study in the Chin-Shan community, Taiwan.<h4>Participants</h4>A total of 2222 participants (54.6±11.9 years, 53.4% women, and 22.4 years of follow-up) who underwent plasma fibrinogen measurements and were without CVD at baseline were recruited, among which 735 participants with available C reactive protein (CRP) were included in the joint analysis of the association of fibrinogen and CRP levels with the risk of CVD.<h4>Primary and secondary outcome measures</h4>Fibrinogen and CRP levels were measured by clotting and high-sensitivity immunoBMJ openAssociations between fibrinogen levels and the risk of cardiovascular disease and all-cause death: a cohort study from the Chin-Shan community in Taiwan.PMC8977805MOST 106-2813-C-002-128-BMOST 106-2314-B-002-158-MY3MOST 103-2314-B-002-135-MY3Chen MFChien KLLee YTHsu HCSu TCLin HJHsieh CTfalseAssociations between fibrinogen levels and the risk of cardiovascular disease and all-cause death: a cohort study from the Chin-Shan community in Taiwan.<h4>Objectives</h4>Although several studies have investigated the association between fibrinogen level and the risk of cardiovascular disease (CVD), few studies have been conducted in Asia.<h4>Setting</h4>We conducted a community-based prospective cohort study in the Chin-Shan community, Taiwan.<h4>Participants</h4>A total of 2222 participants (54.6±11.9 years, 53.4% women, and 22.4 years of follow-up) who underwent plasma fibrinogen measurements and were without CVD at baseline were recruited, among which 735 participants with available C reactive protein (CRP) were included in the joint analysis of the association of fibrinogen and CRP levels with the risk of CVD.<h4>Primary and secondary outcome measures</h4>Fibrinogen and CRP levels were measured by clotting and high-sensitivity immuno2022-01-01T00:00:00Z2022 Apr2025-04-25T18:01:39.721Z2025-04-25T18:01:39.721ZS-EPMC89778053536552610.1136/bmjopen-2021-054638