{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["9(4)"],"submitter":["Akinbosede D"],"pubmed_abstract":["Not all treasure is silver and gold; for pathogenic bacteria, iron is the most precious and the most pillaged of metallic elements. Iron is essential for the survival and growth of all life; however free iron is scarce for bacteria inside human hosts. As a mechanism of defence, humans have evolved ways to store iron so as to render it inaccessible for invading pathogens, such as keeping the metal bound to iron-carrying proteins. For bacteria to survive within humans, they must therefore evolve counters to this defence to compete with these proteins for iron binding, or directly steal iron from them. The most populous form of iron in humans is haem: a functionally significant coordination complex that is central to oxygen transport and predominantly bound by haemoglobin. Haemoglobin is ther"],"journal":["Microbial cell (Graz, Austria)"],"pagination":["84-102"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8977872"],"repository":["biostudies-literature"],"pubmed_title":["Pirates of the haemoglobin."],"pmcid":["PMC8977872"],"pubmed_authors":["Akinbosede D","Hare SA","Chizea R"],"additional_accession":[]},"is_claimable":false,"name":"Pirates of the haemoglobin.","description":"Not all treasure is silver and gold; for pathogenic bacteria, iron is the most precious and the most pillaged of metallic elements. Iron is essential for the survival and growth of all life; however free iron is scarce for bacteria inside human hosts. As a mechanism of defence, humans have evolved ways to store iron so as to render it inaccessible for invading pathogens, such as keeping the metal bound to iron-carrying proteins. For bacteria to survive within humans, they must therefore evolve counters to this defence to compete with these proteins for iron binding, or directly steal iron from them. The most populous form of iron in humans is haem: a functionally significant coordination complex that is central to oxygen transport and predominantly bound by haemoglobin. Haemoglobin is ther","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Apr","modification":"2025-04-25T16:50:29.265Z","creation":"2024-11-05T18:31:32.726Z"},"accession":"S-EPMC8977872","cross_references":{"pubmed":["35434122"],"doi":["10.15698/mic2022.04.775"]}}